Association of long-term tacrolimus (FK506) therapy with abnormal megakaryocytosis, bone marrow fibrosis, and dyserythropoiesis

Haematopoietic abnormalities associated with tacrolimus are relatively rare with reversible pure red cell aplasia being the most common. We report for the first time, to our best knowledge, tacrolimus therapy associated with bone marrow fibrosis, abnormal megakaryocytosis, and dyserythopoiesis in a...

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Detalles Bibliográficos
Autores principales: Yang, Zhongbo, Loew, Thomas, Hammer, Richard D
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Ltd 2015
Materias:
Case Reports
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4527820/
https://www.ncbi.nlm.nih.gov/pubmed/26273466
http://dx.doi.org/10.1002/ccr3.303
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author Yang, Zhongbo
Loew, Thomas
Hammer, Richard D
author_facet Yang, Zhongbo
Loew, Thomas
Hammer, Richard D
author_sort Yang, Zhongbo
collection PubMed
description Haematopoietic abnormalities associated with tacrolimus are relatively rare with reversible pure red cell aplasia being the most common. We report for the first time, to our best knowledge, tacrolimus therapy associated with bone marrow fibrosis, abnormal megakaryocytosis, and dyserythopoiesis in a 17-year-old male treated with tacrolimus for nephrotic syndrome.
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spelling pubmed-45278202015-08-13 Association of long-term tacrolimus (FK506) therapy with abnormal megakaryocytosis, bone marrow fibrosis, and dyserythropoiesis Yang, Zhongbo Loew, Thomas Hammer, Richard D Clin Case Rep Case Reports Haematopoietic abnormalities associated with tacrolimus are relatively rare with reversible pure red cell aplasia being the most common. We report for the first time, to our best knowledge, tacrolimus therapy associated with bone marrow fibrosis, abnormal megakaryocytosis, and dyserythopoiesis in a 17-year-old male treated with tacrolimus for nephrotic syndrome. John Wiley & Sons, Ltd 2015-07 2015-06-13 /pmc/articles/PMC4527820/ /pubmed/26273466 http://dx.doi.org/10.1002/ccr3.303 Text en © 2015 The Authors. Clinical Case Reports published by John Wiley & Sons Ltd. http://creativecommons.org/licenses/by-nc/4.0/ This is an open access article under the terms of the Creative Commons Attribution-NonCommercial License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited and is not used for commercial purposes.
spellingShingle Case Reports
Yang, Zhongbo
Loew, Thomas
Hammer, Richard D
Association of long-term tacrolimus (FK506) therapy with abnormal megakaryocytosis, bone marrow fibrosis, and dyserythropoiesis
title Association of long-term tacrolimus (FK506) therapy with abnormal megakaryocytosis, bone marrow fibrosis, and dyserythropoiesis
title_full Association of long-term tacrolimus (FK506) therapy with abnormal megakaryocytosis, bone marrow fibrosis, and dyserythropoiesis
title_fullStr Association of long-term tacrolimus (FK506) therapy with abnormal megakaryocytosis, bone marrow fibrosis, and dyserythropoiesis
title_full_unstemmed Association of long-term tacrolimus (FK506) therapy with abnormal megakaryocytosis, bone marrow fibrosis, and dyserythropoiesis
title_short Association of long-term tacrolimus (FK506) therapy with abnormal megakaryocytosis, bone marrow fibrosis, and dyserythropoiesis
title_sort association of long-term tacrolimus (fk506) therapy with abnormal megakaryocytosis, bone marrow fibrosis, and dyserythropoiesis
topic Case Reports
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4527820/
https://www.ncbi.nlm.nih.gov/pubmed/26273466
http://dx.doi.org/10.1002/ccr3.303
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AT hammerrichardd associationoflongtermtacrolimusfk506therapywithabnormalmegakaryocytosisbonemarrowfibrosisanddyserythropoiesis

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