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Nutlin-3a: A Potential Therapeutic Opportunity for TP53 Wild-Type Ovarian Carcinomas
Epithelial ovarian cancer is a diverse molecular and clinical disease, yet standard treatment is the same for all subtypes. TP53 mutations represent a node of divergence in epithelial ovarian cancer histologic subtypes and may represent a therapeutic opportunity in subtypes expressing wild type, inc...
Autores principales: | Crane, Erin K., Kwan, Suet-Yan, Izaguirre, Daisy I., Tsang, Yvonne T. M., Mullany, Lisa K., Zu, Zhifei, Richards, JoAnne S., Gershenson, David M., Wong, Kwong-Kwok |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4527847/ https://www.ncbi.nlm.nih.gov/pubmed/26248031 http://dx.doi.org/10.1371/journal.pone.0135101 |
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