Cargando…

Erythropoietin dampens injury-induced microglial motility

Traumatic brain injury causes progressive brain atrophy and cognitive decline. Surprisingly, an early treatment with erythropoietin (EPO) prevents these consequences of secondary neurodegeneration, but the mechanisms have remained obscure. Here we show by advanced imaging and innovative analytical t...

Descripción completa

Detalles Bibliográficos
Autores principales:	Mitkovski, Miso, Dahm, Liane, Heinrich, Ralf, Monnheimer, Mathieu, Gerhart, Simone, Stegmüller, Judith, Hanisch, Uwe-Karsten, Nave, Klaus-Armin, Ehrenreich, Hannelore
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2015
Materias:	Brief Communication
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4527993/ https://www.ncbi.nlm.nih.gov/pubmed/25966953 http://dx.doi.org/10.1038/jcbfm.2015.100

Ejemplares similares

The Insect Ortholog of the Human Orphan Cytokine Receptor CRLF3 Is a Neuroprotective Erythropoietin Receptor
por: Hahn, Nina, et al.
Publicado: (2017)

Microglial diversity by responses and responders
por: Gertig, Ulla, et al.
Publicado: (2014)

For decades against the mainstream − From erythropoietin and hypoxia as novel treatment strategies to deep phenotyping in neuropsychiatric disorders
por: Ehrenreich, Hannelore
Publicado: (2022)

Phenotype-Based Genetic Association Studies (PGAS)—Towards Understanding the Contribution of Common Genetic Variants to Schizophrenia Subphenotypes
por: Ehrenreich, Hannelore, et al.
Publicado: (2014)

Expression of constitutively active erythropoietin receptor in pyramidal neurons of cortex and hippocampus boosts higher cognitive functions in mice
por: Sargin, Derya, et al.
Publicado: (2011)

Erythropoietin improves operant conditioning and stability of cognitive performance in mice
por: El-Kordi, Ahmed, et al.
Publicado: (2009)

The SocioBox: A Novel Paradigm to Assess Complex Social Recognition in Male Mice
por: Krueger-Burg, Dilja, et al.
Publicado: (2016)

Erythropoietin re-wires cognition-associated transcriptional networks
por: Singh, Manvendra, et al.
Publicado: (2023)

Vascular response to social cognitive performance measured by infrared thermography: A translational study from mouse to man
por: Seidel, Jan, et al.
Publicado: (2019)

EV-3, an endogenous human erythropoietin isoform with distinct functional relevance
por: Bonnas, Christel, et al.
Publicado: (2017)

Functional hypoxia drives neuroplasticity and neurogenesis via brain erythropoietin
por: Wakhloo, Debia, et al.
Publicado: (2020)

Erythropoietin as candidate for supportive treatment of severe COVID-19
por: Ehrenreich, Hannelore, et al.
Publicado: (2020)

Revisiting adult neurogenesis and the role of erythropoietin for neuronal and oligodendroglial differentiation in the hippocampus
por: Hassouna, I, et al.
Publicado: (2016)

Introducing the brain erythropoietin circle to explain adaptive brain hardware upgrade and improved performance
por: Ehrenreich, Hannelore, et al.
Publicado: (2022)

Heterozygous Ambra1 Deficiency in Mice: A Genetic Trait with Autism-Like Behavior Restricted to the Female Gender
por: Dere, Ekrem, et al.
Publicado: (2014)

Alternative Erythropoietin Receptors in the Nervous System
por: Ostrowski, Daniela, et al.
Publicado: (2018)

Effects of erythropoietin on depressive symptoms and neurocognitive deficits in depression and bipolar disorder
por: Miskowiak, Kamilla W, et al.
Publicado: (2010)

Addressing the ‘hypoxia paradox’ in severe COVID-19: literature review and report of four cases treated with erythropoietin analogues
por: Begemann, Martin, et al.
Publicado: (2021)

Erythropoietin enhances hippocampal long-term potentiation and memory
por: Adamcio, Bartosz, et al.
Publicado: (2008)

To dampen demyelination
por: Maxmen, Amy
Publicado: (2010)

Exploiting moderate hypoxia to benefit patients with brain disease: Molecular mechanisms and translational research in progress
por: Ehrenreich, Hannelore, et al.
Publicado: (2023)

Activin A increases phagocytosis of Escherichia coli K1 by primary murine microglial cells activated by toll-like receptor agonists
por: Diesselberg, Catharina, et al.
Publicado: (2018)

A critical role for erythropoietin on vagus nerve Schwann cells in intestinal motility
por: Govindappa, Prem Kumar, et al.
Publicado: (2023)

Molecular Mechanisms of Microglial Motility: Changes in Ageing and Alzheimer’s Disease
por: Franco-Bocanegra, Diana K., et al.
Publicado: (2019)

Erythropoietin Enhances Post-ischemic Migration and Phagocytosis and Alleviates the Activation of Inflammasomes in Human Microglial Cells
por: Arik, Eren, et al.
Publicado: (2022)

Axonal degeneration in an Alzheimer mouse model is PS1 gene dose dependent and linked to intraneuronal Aβ accumulation
por: Christensen, Ditte Z., et al.
Publicado: (2014)

Autism as a disease of the synapse: search for mechanistic insight
por: Ehrenreich, Hannelore
Publicado: (2015)

Autoantibodies against N-methyl-d-aspartate receptor 1 in health and disease
por: Ehrenreich, Hannelore
Publicado: (2018)

Autoantibodies against the N-Methyl-d-Aspartate Receptor Subunit NR1: Untangling Apparent Inconsistencies for Clinical Practice
por: Ehrenreich, Hannelore
Publicado: (2017)

Spinal microglial motility is independent of neuronal activity and plasticity in adult mice
por: Chen, Tao, et al.
Publicado: (2010)

Functional diversity of microglia – how heterogeneous are they to begin with?
por: Hanisch, Uwe-Karsten
Publicado: (2013)

High Prevalence of Carbapenemase-Producing Acinetobacter baumannii in Wound Infections, Ghana, 2017/2018
por: Monnheimer, Mathieu, et al.
Publicado: (2021)

Splenic schooling dampens inflammation
por: Van Epps, Heather L.
Publicado: (2006)

Sweet inhibitor DAMPens sepsis
por: Paulson, James C., et al.
Publicado: (2011)

Plasminogen activator inhibitor type 1 regulates microglial motility and phagocytic activity
por: Jeon, Hyejin, et al.
Publicado: (2012)

Deciphering Resting Microglial Morphology and Process Motility from a Synaptic Prospect
por: Hristovska, Ines, et al.
Publicado: (2016)

Intravenously delivered multilineage-differentiating stress enduring cells dampen excessive glutamate metabolism and microglial activation in experimental perinatal hypoxic ischemic encephalopathy
por: Suzuki, Toshihiko, et al.
Publicado: (2020)

Effects of recombinant human erythropoietin on cognition and neural activity in remitted patients with mood disorders and first-degree relatives of patients with psychiatric disorders: a study protocol for a randomized controlled trial
por: Petersen, Jeff Zarp, et al.
Publicado: (2018)

Neuronal Hyperactivity Disturbs ATP Microgradients, Impairs Microglial Motility, and Reduces Phagocytic Receptor Expression Triggering Apoptosis/Microglial Phagocytosis Uncoupling
por: Abiega, Oihane, et al.
Publicado: (2016)

SP7 gene silencing dampens bone marrow stromal cell hypertrophy, but it also dampens chondrogenesis
por: Franco, Rose Ann G, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_2d0tr7m5strgtbf9ubr47h58tp