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Generating a Metal-responsive Transcriptional Regulator to Test What Confers Metal Sensing in Cells
FrmR from Salmonella enterica serovar typhimurium (a CsoR/RcnR-like transcriptional de-repressor) is shown to repress the frmRA operator-promoter, and repression is alleviated by formaldehyde but not manganese, iron, cobalt, nickel, copper, or Zn(II) within cells. In contrast, repression by a mutant...
Autores principales: | Osman, Deenah, Piergentili, Cecilia, Chen, Junjun, Chakrabarti, Buddhapriya, Foster, Andrew W., Lurie-Luke, Elena, Huggins, Thomas G., Robinson, Nigel J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Biochemistry and Molecular Biology
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4528141/ https://www.ncbi.nlm.nih.gov/pubmed/26109070 http://dx.doi.org/10.1074/jbc.M115.663427 |
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