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In adenosine A(2B) knockouts acute treatment with inorganic nitrate improves glucose disposal, oxidative stress, and AMPK signaling in the liver
Rationale: Accumulating studies suggest that nitric oxide (NO) deficiency and oxidative stress are central pathological mechanisms in type 2 diabetes (T2D). Recent findings demonstrate therapeutic effects by boosting the nitrate-nitrite-NO pathway, which is an alternative pathway for NO formation. T...
Autores principales: | Peleli, Maria, Hezel, Michael, Zollbrecht, Christa, Persson, A. Erik G., Lundberg, Jon O., Weitzberg, Eddie, Fredholm, Bertil B., Carlström, Mattias |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4528163/ https://www.ncbi.nlm.nih.gov/pubmed/26300787 http://dx.doi.org/10.3389/fphys.2015.00222 |
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