Single-Cell Network Analysis Identifies DDIT3 as a Nodal Lineage Regulator in Hematopoiesis

We explore cell heterogeneity during spontaneous and transcription-factor-driven commitment for network inference in hematopoiesis. Since individual genes display discrete OFF states or a distribution of ON levels, we compute and combine pairwise gene associations from binary and continuous componen...

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Detalles Bibliográficos
Autores principales: Pina, Cristina, Teles, José, Fugazza, Cristina, May, Gillian, Wang, Dapeng, Guo, Yanping, Soneji, Shamit, Brown, John, Edén, Patrik, Ohlsson, Mattias, Peterson, Carsten, Enver, Tariq
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2015
Materias:
Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4528262/
https://www.ncbi.nlm.nih.gov/pubmed/26051941
http://dx.doi.org/10.1016/j.celrep.2015.05.016

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