CRISPR/Cas9 Genome Editing in Caenorhabditis elegans: Evaluation of Templates for Homology-Mediated Repair and Knock-Ins by Homology-Independent DNA Repair

Precise genome editing by the Cas9 nuclease depends on exogenously provided templates for homologous recombination. Here, we compare oligonucleotides with short homology and circular DNA molecules with extensive homology to genomic targets as templates for homology-based repair of CRISPR/Cas9 induce...

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Detalles Bibliográficos
Autores principales: Katic, Iskra, Xu, Lan, Ciosk, Rafal
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Genetics Society of America 2015
Materias:
Investigations
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4528321/
https://www.ncbi.nlm.nih.gov/pubmed/26044730
http://dx.doi.org/10.1534/g3.115.019273

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4528321/
https://www.ncbi.nlm.nih.gov/pubmed/26044730
http://dx.doi.org/10.1534/g3.115.019273

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