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Normal ranges of left ventricular strain in children: a meta-analysis
AIMS: The definition of normal values of two-dimensional speckle-tracking echocardiography derived left ventricular (LV) deformation parameters, is of critical importance for the routine application of this modality in children. The objectives of this study were to perform a meta-analysis of normal...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4528396/ https://www.ncbi.nlm.nih.gov/pubmed/26250696 http://dx.doi.org/10.1186/s12947-015-0029-0 |
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author | Jashari, Haki Rydberg, Annika Ibrahimi, Pranvera Bajraktari, Gani Kryeziu, Lindita Jashari, Fisnik Henein, Michael Y. |
author_facet | Jashari, Haki Rydberg, Annika Ibrahimi, Pranvera Bajraktari, Gani Kryeziu, Lindita Jashari, Fisnik Henein, Michael Y. |
author_sort | Jashari, Haki |
collection | PubMed |
description | AIMS: The definition of normal values of two-dimensional speckle-tracking echocardiography derived left ventricular (LV) deformation parameters, is of critical importance for the routine application of this modality in children. The objectives of this study were to perform a meta-analysis of normal ranges for longitudinal, circumferential and radial strain/strain rate values and to identify confounders that may contribute to differences in reported measures. METHODS AND RESULTS: A systematic search was conducted. Studies describing normal healthy subjects and observational studies that used control groups as a comparison were included. Data were combined using a random-effect model. Effects of demographic, clinical and equipment variables were assessed through meta-regression. The search identified 1,192 subjects form 28 articles. Longitudinal strain (LS) normal mean values varied from -12.9 to -26.5 (mean, -20.5; 95% CI, -20.0 to -21.0). Normal mean values of circumferential strain (CS) varied from -10.5 to -27.0 (mean, -22.06; 95% CI, -21.5 to -22.5). Radial strain (RS) normal mean values varied from 24.9 to 62.1 (mean, 45.4; 95% CI, 43.0 to 47.8). Meta-regression showed LV end diastolic diameter as a significant determinant of variation for LS. Longitudinal systolic strain rate (LSRs) was significantly determined by the age and RS by the type of vendor used. CONCLUSION: Variations among different normal ranges were dependent on the vendor used, LV end-diastolic diameter and age. Vendor-independent software for analyzing myocardial deformation in children, using images from different vendors would be the ideal solution for strain measurements or else using the same system for patient’s follow up. |
format | Online Article Text |
id | pubmed-4528396 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2015 |
publisher | BioMed Central |
record_format | MEDLINE/PubMed |
spelling | pubmed-45283962015-08-08 Normal ranges of left ventricular strain in children: a meta-analysis Jashari, Haki Rydberg, Annika Ibrahimi, Pranvera Bajraktari, Gani Kryeziu, Lindita Jashari, Fisnik Henein, Michael Y. Cardiovasc Ultrasound Review AIMS: The definition of normal values of two-dimensional speckle-tracking echocardiography derived left ventricular (LV) deformation parameters, is of critical importance for the routine application of this modality in children. The objectives of this study were to perform a meta-analysis of normal ranges for longitudinal, circumferential and radial strain/strain rate values and to identify confounders that may contribute to differences in reported measures. METHODS AND RESULTS: A systematic search was conducted. Studies describing normal healthy subjects and observational studies that used control groups as a comparison were included. Data were combined using a random-effect model. Effects of demographic, clinical and equipment variables were assessed through meta-regression. The search identified 1,192 subjects form 28 articles. Longitudinal strain (LS) normal mean values varied from -12.9 to -26.5 (mean, -20.5; 95% CI, -20.0 to -21.0). Normal mean values of circumferential strain (CS) varied from -10.5 to -27.0 (mean, -22.06; 95% CI, -21.5 to -22.5). Radial strain (RS) normal mean values varied from 24.9 to 62.1 (mean, 45.4; 95% CI, 43.0 to 47.8). Meta-regression showed LV end diastolic diameter as a significant determinant of variation for LS. Longitudinal systolic strain rate (LSRs) was significantly determined by the age and RS by the type of vendor used. CONCLUSION: Variations among different normal ranges were dependent on the vendor used, LV end-diastolic diameter and age. Vendor-independent software for analyzing myocardial deformation in children, using images from different vendors would be the ideal solution for strain measurements or else using the same system for patient’s follow up. BioMed Central 2015-08-07 /pmc/articles/PMC4528396/ /pubmed/26250696 http://dx.doi.org/10.1186/s12947-015-0029-0 Text en © Jashari et al. 2015 This article is published under license to BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated. |
spellingShingle | Review Jashari, Haki Rydberg, Annika Ibrahimi, Pranvera Bajraktari, Gani Kryeziu, Lindita Jashari, Fisnik Henein, Michael Y. Normal ranges of left ventricular strain in children: a meta-analysis |
title | Normal ranges of left ventricular strain in children: a meta-analysis |
title_full | Normal ranges of left ventricular strain in children: a meta-analysis |
title_fullStr | Normal ranges of left ventricular strain in children: a meta-analysis |
title_full_unstemmed | Normal ranges of left ventricular strain in children: a meta-analysis |
title_short | Normal ranges of left ventricular strain in children: a meta-analysis |
title_sort | normal ranges of left ventricular strain in children: a meta-analysis |
topic | Review |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4528396/ https://www.ncbi.nlm.nih.gov/pubmed/26250696 http://dx.doi.org/10.1186/s12947-015-0029-0 |
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