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Estimating T-cell repertoire diversity: limitations of classical estimators and a new approach

A highly diverse T-cell receptor (TCR) repertoire is a fundamental property of an effective immune system, and is associated with efficient control of viral infections and other pathogens. However, direct measurement of total TCR diversity is impossible. The diversity is high and the frequency distr...

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Detalles Bibliográficos
Autores principales:	Laydon, Daniel J., Bangham, Charles R. M., Asquith, Becca
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The Royal Society 2015
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4528489/ https://www.ncbi.nlm.nih.gov/pubmed/26150657 http://dx.doi.org/10.1098/rstb.2014.0291

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