Magnetic separation-based blood purification: a promising new approach for the removal of disease-causing compounds?

Recent studies report promising results regarding extracorporeal magnetic separation-based blood purification for the rapid and selective removal of disease-causing compounds from whole blood. High molecular weight compounds, bacteria and cells can be eliminated from blood within minutes, hence offe...

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Detalles Bibliográficos
Autores principales: Herrmann, I K, Schlegel, A A, Graf, R, Stark, W J, Beck-Schimmer, Beatrice
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4528690/
https://www.ncbi.nlm.nih.gov/pubmed/26253109
http://dx.doi.org/10.1186/s12951-015-0110-8
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author Herrmann, I K
Schlegel, A A
Graf, R
Stark, W J
Beck-Schimmer, Beatrice
author_facet Herrmann, I K
Schlegel, A A
Graf, R
Stark, W J
Beck-Schimmer, Beatrice
author_sort Herrmann, I K
collection PubMed
description Recent studies report promising results regarding extracorporeal magnetic separation-based blood purification for the rapid and selective removal of disease-causing compounds from whole blood. High molecular weight compounds, bacteria and cells can be eliminated from blood within minutes, hence offering novel treatment strategies for the management of intoxications and blood stream infections. However, risks associated with incomplete particle separation and the biological consequences of particles entering circulation remain largely unclear. This article discusses the promising future of magnetic separation-based purification while keeping important safety considerations in mind.
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spelling pubmed-45286902015-08-08 Magnetic separation-based blood purification: a promising new approach for the removal of disease-causing compounds? Herrmann, I K Schlegel, A A Graf, R Stark, W J Beck-Schimmer, Beatrice J Nanobiotechnology Review Recent studies report promising results regarding extracorporeal magnetic separation-based blood purification for the rapid and selective removal of disease-causing compounds from whole blood. High molecular weight compounds, bacteria and cells can be eliminated from blood within minutes, hence offering novel treatment strategies for the management of intoxications and blood stream infections. However, risks associated with incomplete particle separation and the biological consequences of particles entering circulation remain largely unclear. This article discusses the promising future of magnetic separation-based purification while keeping important safety considerations in mind. BioMed Central 2015-08-08 /pmc/articles/PMC4528690/ /pubmed/26253109 http://dx.doi.org/10.1186/s12951-015-0110-8 Text en © Herrmann et al. 2015 Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.
spellingShingle Review
Herrmann, I K
Schlegel, A A
Graf, R
Stark, W J
Beck-Schimmer, Beatrice
Magnetic separation-based blood purification: a promising new approach for the removal of disease-causing compounds?
title Magnetic separation-based blood purification: a promising new approach for the removal of disease-causing compounds?
title_full Magnetic separation-based blood purification: a promising new approach for the removal of disease-causing compounds?
title_fullStr Magnetic separation-based blood purification: a promising new approach for the removal of disease-causing compounds?
title_full_unstemmed Magnetic separation-based blood purification: a promising new approach for the removal of disease-causing compounds?
title_short Magnetic separation-based blood purification: a promising new approach for the removal of disease-causing compounds?
title_sort magnetic separation-based blood purification: a promising new approach for the removal of disease-causing compounds?
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4528690/
https://www.ncbi.nlm.nih.gov/pubmed/26253109
http://dx.doi.org/10.1186/s12951-015-0110-8
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