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Metachronous tubulovillous and tubular adenomas of the anal canal
Anal canal adenoma is an extremely rare disease that has the potential to transform into a malignant tumor. We herein presented a rare case of metachronous multiple adenomas of the anal canal. A 48-year-old woman underwent total colonoscopy following a positive fecal blood test. A 9-mm villous polyp...
Autores principales: | , , , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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BioMed Central
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4528720/ https://www.ncbi.nlm.nih.gov/pubmed/26249723 http://dx.doi.org/10.1186/s13000-015-0379-9 |
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author | Nozawa, Hiroaki Ishihara, Soichiro Morikawa, Teppei Tanaka, Junichiro Yasuda, Koji Ohtani, Kensuke Nishikawa, Takeshi Tanaka, Toshiaki Kiyomatsu, Tomomichi Kawai, Kazushige Hata, Keisuke Kazama, Shinsuke Yamaguchi, Hironori Sunami, Eiji Kitayama, Joji Fukayama, Masashi Watanabe, Toshiaki |
author_facet | Nozawa, Hiroaki Ishihara, Soichiro Morikawa, Teppei Tanaka, Junichiro Yasuda, Koji Ohtani, Kensuke Nishikawa, Takeshi Tanaka, Toshiaki Kiyomatsu, Tomomichi Kawai, Kazushige Hata, Keisuke Kazama, Shinsuke Yamaguchi, Hironori Sunami, Eiji Kitayama, Joji Fukayama, Masashi Watanabe, Toshiaki |
author_sort | Nozawa, Hiroaki |
collection | PubMed |
description | Anal canal adenoma is an extremely rare disease that has the potential to transform into a malignant tumor. We herein presented a rare case of metachronous multiple adenomas of the anal canal. A 48-year-old woman underwent total colonoscopy following a positive fecal blood test. A 9-mm villous polyp arising from the posterior wall of the anal canal was removed by snare polypectomy. Histologically, the tumor was tubulovillous adenoma with high-grade dysplasia and the cut end was negative for tumor cells. Six years later, an elevated lesion, macroscopically five millimeters in size, was detected in the left wall of the anal canal in a follow-up colonoscopy. Local excision of the tumor was performed, and the lesion was pathologically confirmed to be tubular adenoma with high-grade dysplasia limited to the mucosa. The patient is currently alive without any evidence of recurrence for six months after surgery. Although she had a past history of cervical cancer, the multiple tumors arising in the anal canal were unlikely to be related to human papilloma virus infection. Our case report underscores the importance of careful observations throughout colonoscopy to detect precancerous lesions, particularly in anatomically narrow segments. |
format | Online Article Text |
id | pubmed-4528720 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2015 |
publisher | BioMed Central |
record_format | MEDLINE/PubMed |
spelling | pubmed-45287202015-08-08 Metachronous tubulovillous and tubular adenomas of the anal canal Nozawa, Hiroaki Ishihara, Soichiro Morikawa, Teppei Tanaka, Junichiro Yasuda, Koji Ohtani, Kensuke Nishikawa, Takeshi Tanaka, Toshiaki Kiyomatsu, Tomomichi Kawai, Kazushige Hata, Keisuke Kazama, Shinsuke Yamaguchi, Hironori Sunami, Eiji Kitayama, Joji Fukayama, Masashi Watanabe, Toshiaki Diagn Pathol Case Report Anal canal adenoma is an extremely rare disease that has the potential to transform into a malignant tumor. We herein presented a rare case of metachronous multiple adenomas of the anal canal. A 48-year-old woman underwent total colonoscopy following a positive fecal blood test. A 9-mm villous polyp arising from the posterior wall of the anal canal was removed by snare polypectomy. Histologically, the tumor was tubulovillous adenoma with high-grade dysplasia and the cut end was negative for tumor cells. Six years later, an elevated lesion, macroscopically five millimeters in size, was detected in the left wall of the anal canal in a follow-up colonoscopy. Local excision of the tumor was performed, and the lesion was pathologically confirmed to be tubular adenoma with high-grade dysplasia limited to the mucosa. The patient is currently alive without any evidence of recurrence for six months after surgery. Although she had a past history of cervical cancer, the multiple tumors arising in the anal canal were unlikely to be related to human papilloma virus infection. Our case report underscores the importance of careful observations throughout colonoscopy to detect precancerous lesions, particularly in anatomically narrow segments. BioMed Central 2015-08-07 /pmc/articles/PMC4528720/ /pubmed/26249723 http://dx.doi.org/10.1186/s13000-015-0379-9 Text en © Nozawa et al. 2015 Open Access This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated. |
spellingShingle | Case Report Nozawa, Hiroaki Ishihara, Soichiro Morikawa, Teppei Tanaka, Junichiro Yasuda, Koji Ohtani, Kensuke Nishikawa, Takeshi Tanaka, Toshiaki Kiyomatsu, Tomomichi Kawai, Kazushige Hata, Keisuke Kazama, Shinsuke Yamaguchi, Hironori Sunami, Eiji Kitayama, Joji Fukayama, Masashi Watanabe, Toshiaki Metachronous tubulovillous and tubular adenomas of the anal canal |
title | Metachronous tubulovillous and tubular adenomas of the anal canal |
title_full | Metachronous tubulovillous and tubular adenomas of the anal canal |
title_fullStr | Metachronous tubulovillous and tubular adenomas of the anal canal |
title_full_unstemmed | Metachronous tubulovillous and tubular adenomas of the anal canal |
title_short | Metachronous tubulovillous and tubular adenomas of the anal canal |
title_sort | metachronous tubulovillous and tubular adenomas of the anal canal |
topic | Case Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4528720/ https://www.ncbi.nlm.nih.gov/pubmed/26249723 http://dx.doi.org/10.1186/s13000-015-0379-9 |
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