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Expression of chicken interleukin-2 by a highly virulent strain of Newcastle disease virus leads to decreased systemic viral load but does not significantly affect mortality in chickens

BACKGROUND: In mammals, interleukin 2 (IL-2) has been shown to decrease replication or attenuate pathogenicity of numerous viral pathogens (herpes simplex virus, vaccinia virus, human respiratory syncytial virus, human immunodeficiency virus) by activating natural killer cells (NK), cytotoxic T lymp...

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Detalles Bibliográficos
Autores principales:	Susta, Leonardo, Diel, Diego G., Courtney, Sean, Cardenas-Garcia, Stivalis, Sundick, Roy S., Miller, Patti J., Brown, Corrie C., Afonso, Claudio L.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2015
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4528788/ https://www.ncbi.nlm.nih.gov/pubmed/26253150 http://dx.doi.org/10.1186/s12985-015-0353-x

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