Drug-Induced Liver Injury by Glatiramer Acetate Used for Treatment of Multiple Sclerosis: A Case Report

Glatiramer acetate (GA, Copaxone) is an approved drug for the treatment of relapsing–remitting multiple sclerosis. Most common side effects observed with GA are local injection site reactions, which can include pain, swelling, or redness. However, systemic adverse event such as hepatotoxicity relate...

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Detalles Bibliográficos
Autores principales: Onmez, Attila, Eminler, Ahmet Tarik, Ergenç, Hasan, Baykara, Meltem, Uslan, Ihsan, Tamer, Ali
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2013
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4528838/
https://www.ncbi.nlm.nih.gov/pubmed/26425591
http://dx.doi.org/10.1177/2324709613517493
Descripción
Sumario:Glatiramer acetate (GA, Copaxone) is an approved drug for the treatment of relapsing–remitting multiple sclerosis. Most common side effects observed with GA are local injection site reactions, which can include pain, swelling, or redness. However, systemic adverse event such as hepatotoxicity related to GA is rarely seen. In this report, we present a case of GA-induced toxic hepatitis associated with cholestatic and hepatocellular damage.

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