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Histological Regression of Giant Cell Tumor of Bone Following RANK Ligand Inhibition

Lung metastases are a rare complication of giant cell tumors of bone. We herein describe an interesting case of histological regression and size reduction of lung metastases originating from a primary giant cell tumor of bone in response to the RANK ligand inhibitor denosumab.

Detalles Bibliográficos
Autores principales: Dietrich, Martin F., Cavuoti, Dominick, Landay, Michael, Arriaga, Yull E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4528877/
https://www.ncbi.nlm.nih.gov/pubmed/26425630
http://dx.doi.org/10.1177/2324709614560216
Descripción
Sumario:Lung metastases are a rare complication of giant cell tumors of bone. We herein describe an interesting case of histological regression and size reduction of lung metastases originating from a primary giant cell tumor of bone in response to the RANK ligand inhibitor denosumab.