Cargando…

Antileukemic Efficacy of Continuous vs Discontinuous Dexamethasone in Murine Models of Acute Lymphoblastic Leukemia

Osteonecrosis is one of the most common, serious, toxicities resulting from the treatment of acute lymphoblastic leukemia. In recent years, pediatric acute lymphoblastic leukemia clinical trials have used discontinuous rather than continuous dosing of dexamethasone in an effort to reduce the inciden...

Descripción completa

Detalles Bibliográficos
Autores principales:	Ramsey, Laura B., Janke, Laura J., Payton, Monique A., Cai, Xiangjun, Paugh, Steven W., Karol, Seth E., Kamdem, Landry Kamdem, Cheng, Cheng, Williams, Richard T., Jeha, Sima, Pui, Ching-Hon, Evans, William E., Relling, Mary V.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2015
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4529108/ https://www.ncbi.nlm.nih.gov/pubmed/26252865 http://dx.doi.org/10.1371/journal.pone.0135134

Ejemplares similares

Asparaginase combined with discontinuous dexamethasone improves antileukemic efficacy without increasing osteonecrosis in preclinical models
por: Karol, Seth E., et al.
Publicado: (2019)

Fenofibrate reduces osteonecrosis without affecting antileukemic efficacy in dexamethasone-treated mice
por: Finch, Emily R., et al.
Publicado: (2020)

Genetics of ancestry-specific risk for relapse in acute lymphoblastic leukemia
por: Karol, Seth E., et al.
Publicado: (2017)

Antileukemic properties of the kinase inhibitor OTSSP167 in T-cell acute lymphoblastic leukemia
por: Bridges, Cory Seth, et al.
Publicado: (2022)

Comprehensive analysis of dose intensity of acute lymphoblastic leukemia chemotherapy
por: Karol, Seth E., et al.
Publicado: (2021)

Fluoroquinolone prophylaxis does not increase risk of neuropathy in children with acute lymphoblastic leukemia
por: Karol, Seth E., et al.
Publicado: (2020)

1155. Covering Your Tracts? The Effect of Antibiotic Prophylaxis on Respiratory Tract Infections in Pediatric Acute Lymphoblastic Leukemia
por: Strength, Rachel, et al.
Publicado: (2021)

Pharmacotypes across the genomic landscape of pediatric acute lymphoblastic leukemia and impact on treatment response
por: Lee, Shawn H. R., et al.
Publicado: (2023)

Personalized therapy in pediatric high-risk B-cell acute lymphoblastic leukemia
por: Karol, Seth E., et al.
Publicado: (2020)

The effect of body mass index at diagnosis on clinical outcome in children with newly diagnosed acute lymphoblastic leukemia
por: Eissa, H M, et al.
Publicado: (2017)

Targeting lactate dehydrogenase A (LDHA) exerts antileukemic effects on T‐cell acute lymphoblastic leukemia
por: Yu, Haizhi, et al.
Publicado: (2020)

Clinical Impact of Minimal Residual Disease in Children with Different Subtypes of Acute Lymphoblastic Leukemia Treated with Response-Adapted Therapy
por: Pui, Ching-Hon, et al.
Publicado: (2016)

Modeling Mechanisms of In Vivo Variability in Methotrexate Accumulation and Folate Pathway Inhibition in Acute Lymphoblastic Leukemia Cells
por: Panetta, John C., et al.
Publicado: (2010)

Dronabinol has preferential antileukemic activity in acute lymphoblastic and myeloid leukemia with lymphoid differentiation patterns
por: Kampa-Schittenhelm, Kerstin Maria, et al.
Publicado: (2016)

Decitabine demonstrates antileukemic activity in B cell precursor acute lymphoblastic leukemia with MLL rearrangements
por: Roolf, C., et al.
Publicado: (2018)

Concordance between glucose-6-phosphate dehydrogenase (G6PD) genotype and phenotype and rasburicase use in patients with hematologic malignancies
por: Robinson, Katherine M., et al.
Publicado: (2018)

Vaccines against SARS‐CoV‐2 are safe to administer in patients with antibodies to pegaspargase
por: Swanson, Hope D., et al.
Publicado: (2022)

Functional investigation of inherited noncoding genetic variation impacting the pharmacogenomics of childhood acute lymphoblastic leukemia treatment
por: Bhattarai, Kashi Raj, et al.
Publicado: (2023)

A Revised Definition for Cure of Childhood Acute Lymphoblastic Leukemia
por: Pui, CH, et al.
Publicado: (2014)

Population PK/PD Model of Homocysteine Concentrations after High-Dose Methotrexate Treatment in Patients with Acute Lymphoblastic Leukemia
por: Rühs, Hauke, et al.
Publicado: (2012)

A p53-regulated apoptotic gene signature predicts treatment response and outcome in pediatric acute lymphoblastic leukemia
por: Bainer, Russell O, et al.
Publicado: (2017)

Identification of small molecules that mitigate vincristine‐induced neurotoxicity while sensitizing leukemia cells to vincristine
por: Diouf, Barthelemy, et al.
Publicado: (2021)

Precision medicine in acute lymphoblastic leukemia
por: Pui, Ching-Hon
Publicado: (2020)

Clofarabine treatment of KMT2Ar infantile patients with acute lymphoblastic leukemia in St. Jude Total Therapy Study 16
por: Gruber, Tanja A., et al.
Publicado: (2022)

Role of Vitamins A and D in BCR-ABL Arf(−/−) Acute Lymphoblastic Leukemia
por: Annu, Kavya, et al.
Publicado: (2020)

Antibiotic prophylaxis and the gastrointestinal resistome in paediatric patients with acute lymphoblastic leukaemia: a cohort study with metagenomic sequencing analysis
por: Margolis, Elisa B, et al.
Publicado: (2021)

Asparaginase Potentiates Glucocorticoid-Induced Osteonecrosis in a Mouse Model
por: Liu, Chengcheng, et al.
Publicado: (2016)

In Vivo Response to Methotrexate Forecasts Outcome of Acute Lymphoblastic Leukemia and Has a Distinct Gene Expression Profile
por: Sorich, Michael J, et al.
Publicado: (2008)

Long-term results of St. Jude Total Therapy studies 11, 12, 13A, 13B and 14 for childhood acute lymphoblastic leukemia
por: Pui, C-H, et al.
Publicado: (2009)

Antileukemic activity of novel adenosine derivatives
por: Poczta, Anastazja, et al.
Publicado: (2019)

Mutual antagonism between glucocorticoid and canonical Wnt signaling pathways in B-cell acute lymphoblastic leukemia
por: Bergeron, Brennan P., et al.
Publicado: (2023)

Erratum to: Between-course targeting of methotrexate exposure using pharmacokinetically guided dosage adjustments
por: Pauley, Jennifer L., et al.
Publicado: (2013)

Between-course targeting of methotrexate exposure using pharmacokinetically guided dosage adjustments
por: Pauley, Jennifer L., et al.
Publicado: (2013)

Epigenomic mapping in B-cell acute lymphoblastic leukemia identifies transcriptional regulators and noncoding variants promoting distinct chromatin architectures
por: Barnett, Kelly R., et al.
Publicado: (2023)

Baicalein Triggers Mitochondria-Mediated Apoptosis and Enhances the Antileukemic Effect of Vincristine in Childhood Acute Lymphoblastic Leukemia CCRF-CEM Cells
por: Chen, Yun-Ju, et al.
Publicado: (2013)

In Situ Stabilisation of Silver Nanoparticles at Chitosan-Functionalised Graphene Oxide for Reduction of 2,4-Dinitrophenol in Water
por: Makaudi, Rebaone, et al.
Publicado: (2021)

Advances in the Diagnosis and Treatment of Pediatric Acute Lymphoblastic Leukemia
por: Inaba, Hiroto, et al.
Publicado: (2021)

Antileukemic Effect of Tualang Honey on Acute and Chronic Leukemia Cell Lines
por: Nik Man, Nik Muhd Khuzaimi, et al.
Publicado: (2015)

Patient-Level Meta-analysis of Clofarabine in Acute Lymphoblastic Leukemia
por: Jeha, Sima, et al.
Publicado: (2023)

Clofarabine exerts antileukemic activity against cytarabine‐resistant B‐cell precursor acute lymphoblastic leukemia with low deoxycytidine kinase expression
por: Huang, Meixian, et al.
Publicado: (2018)

Cannot write session to /tmp/vufind_sessions/sess_09rngdovtks267gcdpkn8alred