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Microglial Activation Promotes Cell Survival in Organotypic Cultures of Postnatal Mouse Retinal Explants
The role of microglia during neurodegeneration remains controversial. We investigated whether microglial cells have a neurotoxic or neuroprotective function in the retina. Retinal explants from 10-day-old mice were treated in vitro with minocycline to inhibit microglial activation, with LPS to incre...
Autores principales: | Ferrer-Martín, Rosa M., Martín-Oliva, David, Sierra-Martín, Ana, Carrasco, Maria-Carmen, Martín-Estebané, María, Calvente, Ruth, Martín-Guerrero, Sandra M., Marín-Teva, José L., Navascués, Julio, Cuadros, Miguel A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4529135/ https://www.ncbi.nlm.nih.gov/pubmed/26252475 http://dx.doi.org/10.1371/journal.pone.0135238 |
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