Molecular Cloning, Heterologous Expression, and Functional Characterization of an NADPH-Cytochrome P450 Reductase Gene from Camptotheca acuminata, a Camptothecin-Producing Plant

Camptothecin (CAM), a complex pentacyclic pyrroloqinoline alkaloid, is the starting material for CAM-type drugs that are well-known antitumor plant drugs. Although many chemical and biological research efforts have been performed to produce CAM, a few attempts have been made to uncover the enzymatic...

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Detalles Bibliográficos
Autores principales: Qu, Xixing, Pu, Xiang, Chen, Fei, Yang, Yun, Yang, Lixia, Zhang, Guolin, Luo, Yinggang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4529168/
https://www.ncbi.nlm.nih.gov/pubmed/26252645
http://dx.doi.org/10.1371/journal.pone.0135397

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4529168/
https://www.ncbi.nlm.nih.gov/pubmed/26252645
http://dx.doi.org/10.1371/journal.pone.0135397

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