Drosophila Longevity Assurance Conferred by Reduced Insulin Receptor Substrate Chico Partially Requires d4eBP

Mutations of the insulin/IGF signaling (IIS) pathway extend Drosophila lifespan. Based on genetic epistasis analyses, this longevity assurance is attributed to downstream effects of the FOXO transcription factor. However, as reported FOXO accounts for only a portion of the observed longevity benefit...

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Detalles Bibliográficos
Autores principales: Bai, Hua, Post, Stephanie, Kang, Ping, Tatar, Marc
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4529185/
https://www.ncbi.nlm.nih.gov/pubmed/26252766
http://dx.doi.org/10.1371/journal.pone.0134415

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4529185/
https://www.ncbi.nlm.nih.gov/pubmed/26252766
http://dx.doi.org/10.1371/journal.pone.0134415

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