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Psychotropic Drug Use in São Paulo, Brazil – An Epidemiological Survey

OBJECTIVE: To estimate the prevalence of one month psychotropic drug use in São Paulo, Brazil, and to assess the gap treatment between the presence of mental disorders and psychotropic drug users. METHOD: A probabilistic sample of non-institutionalized individuals from the general population of São...

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Autores principales: Quintana, Maria Ines, Andreoli, Sergio Baxter, Peluffo, Marcela Poctich, Ribeiro, Wagner Silva, Feijo, Marcelo M., Bressan, Rodrigo Affonseca, Coutinho, Evandro S. F., Mari, Jair de Jesus
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4529275/
https://www.ncbi.nlm.nih.gov/pubmed/26252517
http://dx.doi.org/10.1371/journal.pone.0135059
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author Quintana, Maria Ines
Andreoli, Sergio Baxter
Peluffo, Marcela Poctich
Ribeiro, Wagner Silva
Feijo, Marcelo M.
Bressan, Rodrigo Affonseca
Coutinho, Evandro S. F.
Mari, Jair de Jesus
author_facet Quintana, Maria Ines
Andreoli, Sergio Baxter
Peluffo, Marcela Poctich
Ribeiro, Wagner Silva
Feijo, Marcelo M.
Bressan, Rodrigo Affonseca
Coutinho, Evandro S. F.
Mari, Jair de Jesus
author_sort Quintana, Maria Ines
collection PubMed
description OBJECTIVE: To estimate the prevalence of one month psychotropic drug use in São Paulo, Brazil, and to assess the gap treatment between the presence of mental disorders and psychotropic drug users. METHOD: A probabilistic sample of non-institutionalized individuals from the general population of São Paulo (n = 2336; turnout: 84.5%) who were 15 years or older were interviewed by a trained research staff, applying the Composite International Diagnostic Interview 2.1 (CIDI WHO) (depression, anxiety-phobia, OCD\PTSD, alcoholism sections), and an inventory investigating psychotropic drug use during the 12-month and one-month periods immediately preceding the interview. Logistic models were fitted to investigate associations between psychotropic drug use as well as socio-demographic and clinical variables. RESULTS: The one month prevalence of psychotropic drug use in São Paulo was 5.89%, the most commonly used drugs were antidepressants (3.15%) and tranquilizers (2.67%). A higher consumption of psychotropic drugs (overall, antidepressants and tranquilizers) was observed among women (OR:2.42), older individuals (OR:1.04), individuals with higher levels of formal education (1.06), and individuals with a family (OR:2.29) or personal history of mental illness (OR:3.27). The main psychotropic drug prescribers were psychiatrists (41%), followed by general practitioners (30%); 60% of psychotropic drugs were obtained through a government-run dispensing program. Most individuals who obtained a positive diagnosis on the CIDI 2.1 during the previous month were not using psychotropic medication (85%). Among individuals with a diagnosis of moderate to severe depression, 67.5% were not on any pharmacological treatment. CONCLUSION: There is a change in the type of psychotropic more often used in São Paulo, from benzodiazepines to antidepressants, this event is observed in different cultures. The prevalence of use is similar to other developing countries. Most of the patients presenting a psychiatric illness in the month prior to testing were not receiving any sort of psychiatric medication. This may be explained by a failure to identify cases in primary care, which could be improved (and access to treatment could be facilitated) if professionals received more specialized training in managing cases with mental health problems.
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spelling pubmed-45292752015-08-12 Psychotropic Drug Use in São Paulo, Brazil – An Epidemiological Survey Quintana, Maria Ines Andreoli, Sergio Baxter Peluffo, Marcela Poctich Ribeiro, Wagner Silva Feijo, Marcelo M. Bressan, Rodrigo Affonseca Coutinho, Evandro S. F. Mari, Jair de Jesus PLoS One Research Article OBJECTIVE: To estimate the prevalence of one month psychotropic drug use in São Paulo, Brazil, and to assess the gap treatment between the presence of mental disorders and psychotropic drug users. METHOD: A probabilistic sample of non-institutionalized individuals from the general population of São Paulo (n = 2336; turnout: 84.5%) who were 15 years or older were interviewed by a trained research staff, applying the Composite International Diagnostic Interview 2.1 (CIDI WHO) (depression, anxiety-phobia, OCD\PTSD, alcoholism sections), and an inventory investigating psychotropic drug use during the 12-month and one-month periods immediately preceding the interview. Logistic models were fitted to investigate associations between psychotropic drug use as well as socio-demographic and clinical variables. RESULTS: The one month prevalence of psychotropic drug use in São Paulo was 5.89%, the most commonly used drugs were antidepressants (3.15%) and tranquilizers (2.67%). A higher consumption of psychotropic drugs (overall, antidepressants and tranquilizers) was observed among women (OR:2.42), older individuals (OR:1.04), individuals with higher levels of formal education (1.06), and individuals with a family (OR:2.29) or personal history of mental illness (OR:3.27). The main psychotropic drug prescribers were psychiatrists (41%), followed by general practitioners (30%); 60% of psychotropic drugs were obtained through a government-run dispensing program. Most individuals who obtained a positive diagnosis on the CIDI 2.1 during the previous month were not using psychotropic medication (85%). Among individuals with a diagnosis of moderate to severe depression, 67.5% were not on any pharmacological treatment. CONCLUSION: There is a change in the type of psychotropic more often used in São Paulo, from benzodiazepines to antidepressants, this event is observed in different cultures. The prevalence of use is similar to other developing countries. Most of the patients presenting a psychiatric illness in the month prior to testing were not receiving any sort of psychiatric medication. This may be explained by a failure to identify cases in primary care, which could be improved (and access to treatment could be facilitated) if professionals received more specialized training in managing cases with mental health problems. Public Library of Science 2015-08-07 /pmc/articles/PMC4529275/ /pubmed/26252517 http://dx.doi.org/10.1371/journal.pone.0135059 Text en © 2015 Quintana et al http://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited.
spellingShingle Research Article
Quintana, Maria Ines
Andreoli, Sergio Baxter
Peluffo, Marcela Poctich
Ribeiro, Wagner Silva
Feijo, Marcelo M.
Bressan, Rodrigo Affonseca
Coutinho, Evandro S. F.
Mari, Jair de Jesus
Psychotropic Drug Use in São Paulo, Brazil – An Epidemiological Survey
title Psychotropic Drug Use in São Paulo, Brazil – An Epidemiological Survey
title_full Psychotropic Drug Use in São Paulo, Brazil – An Epidemiological Survey
title_fullStr Psychotropic Drug Use in São Paulo, Brazil – An Epidemiological Survey
title_full_unstemmed Psychotropic Drug Use in São Paulo, Brazil – An Epidemiological Survey
title_short Psychotropic Drug Use in São Paulo, Brazil – An Epidemiological Survey
title_sort psychotropic drug use in são paulo, brazil – an epidemiological survey
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4529275/
https://www.ncbi.nlm.nih.gov/pubmed/26252517
http://dx.doi.org/10.1371/journal.pone.0135059
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