Phase I trial of systemic intravenous infusion of interleukin-13-Pseudomonas exotoxin in patients with metastatic adrenocortical carcinoma

Adrenocortical carcinoma (ACC) is a rare but lethal malignancy without effective current therapy for metastatic disease. IL-13-PE is a recombinant cytotoxin consisting of human interleukin-13 (IL-13) and a truncated form of Pseudomonas exotoxin A (PE). The main objectives of this Phase I dose-escala...

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Detalles Bibliográficos
Autores principales: Liu-Chittenden, Yi, Jain, Meenu, Kumar, Parag, Patel, Dhaval, Aufforth, Rachel, Neychev, Vladimir, Sadowski, Samira, Gara, Sudheer K, Joshi, Bharat H, Cottle-Delisle, Candice, Merkel, Roxanne, Yang, Lily, Miettinen, Markku, Puri, Raj K, Kebebew, Electron
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Ltd 2015
Materias:
Clinical Cancer Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4529344/
https://www.ncbi.nlm.nih.gov/pubmed/25767039
http://dx.doi.org/10.1002/cam4.449

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