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Endovascular stenting in malignant obstruction of superior vena cava

INTRODUCTION: Superior vena cava syndrome (SVCS) is obstruction of blood flow through the SVC. It is a medical emergency and most often manifests in patients with a malignant disease process within the thorax. A patient with SVCS requires immediate diagnostic evaluation and therapy. PRESENTATION OF...

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Autores principales: Hamzik, Julian, Chudej, Juraj, Dzian, Anton, Sokol, Juraj, Kubisz, Peter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4529653/
https://www.ncbi.nlm.nih.gov/pubmed/26150051
http://dx.doi.org/10.1016/j.ijscr.2015.06.017
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author Hamzik, Julian
Chudej, Juraj
Dzian, Anton
Sokol, Juraj
Kubisz, Peter
author_facet Hamzik, Julian
Chudej, Juraj
Dzian, Anton
Sokol, Juraj
Kubisz, Peter
author_sort Hamzik, Julian
collection PubMed
description INTRODUCTION: Superior vena cava syndrome (SVCS) is obstruction of blood flow through the SVC. It is a medical emergency and most often manifests in patients with a malignant disease process within the thorax. A patient with SVCS requires immediate diagnostic evaluation and therapy. PRESENTATION OF CASE: A 33-years-old woman presented with complaints of dyspnoea and chest pain. Computer tomography revealed a large mass in the anterior mediastinum. This mass compressed surrounding structures. Stenting was indicated for early symptoms of SVCS. The diagnosis of Hodgkin’s lymphoma (HL) was confirmed with biopsy. The patient’s stage II HL has been subsequently treated with six cycles of chemotherapy with doxorubicin, bleomycin, vinblastine, dacarbazine (ABVD), followed by radiotherapy. Presently she is doing well. DISCUSSION: Although lymphomas are a common cause of SVCS but almost always SVCS is caused by non-Hodgkin’s lymphoma (NHL). HL despite its common presentation with mediastinal lymphadenopathy rarely causes SVCS. CONCLUSION: Lymphomas are a common cause of SVCS in young age. HL may present as SVCS. Pathological confirmation of diagnosis should be done before initiating therapy while dealing with a case of SVCS. SVC stenting is effective and has few complications in patients with SVCS.
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spelling pubmed-45296532015-08-11 Endovascular stenting in malignant obstruction of superior vena cava Hamzik, Julian Chudej, Juraj Dzian, Anton Sokol, Juraj Kubisz, Peter Int J Surg Case Rep Case Report INTRODUCTION: Superior vena cava syndrome (SVCS) is obstruction of blood flow through the SVC. It is a medical emergency and most often manifests in patients with a malignant disease process within the thorax. A patient with SVCS requires immediate diagnostic evaluation and therapy. PRESENTATION OF CASE: A 33-years-old woman presented with complaints of dyspnoea and chest pain. Computer tomography revealed a large mass in the anterior mediastinum. This mass compressed surrounding structures. Stenting was indicated for early symptoms of SVCS. The diagnosis of Hodgkin’s lymphoma (HL) was confirmed with biopsy. The patient’s stage II HL has been subsequently treated with six cycles of chemotherapy with doxorubicin, bleomycin, vinblastine, dacarbazine (ABVD), followed by radiotherapy. Presently she is doing well. DISCUSSION: Although lymphomas are a common cause of SVCS but almost always SVCS is caused by non-Hodgkin’s lymphoma (NHL). HL despite its common presentation with mediastinal lymphadenopathy rarely causes SVCS. CONCLUSION: Lymphomas are a common cause of SVCS in young age. HL may present as SVCS. Pathological confirmation of diagnosis should be done before initiating therapy while dealing with a case of SVCS. SVC stenting is effective and has few complications in patients with SVCS. Elsevier 2015-06-26 /pmc/articles/PMC4529653/ /pubmed/26150051 http://dx.doi.org/10.1016/j.ijscr.2015.06.017 Text en © 2015 The Authors http://creativecommons.org/licenses/by-nc-nd/4.0/ This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Case Report
Hamzik, Julian
Chudej, Juraj
Dzian, Anton
Sokol, Juraj
Kubisz, Peter
Endovascular stenting in malignant obstruction of superior vena cava
title Endovascular stenting in malignant obstruction of superior vena cava
title_full Endovascular stenting in malignant obstruction of superior vena cava
title_fullStr Endovascular stenting in malignant obstruction of superior vena cava
title_full_unstemmed Endovascular stenting in malignant obstruction of superior vena cava
title_short Endovascular stenting in malignant obstruction of superior vena cava
title_sort endovascular stenting in malignant obstruction of superior vena cava
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4529653/
https://www.ncbi.nlm.nih.gov/pubmed/26150051
http://dx.doi.org/10.1016/j.ijscr.2015.06.017
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