Koumine enhances spinal cord 3α-hydroxysteroid oxidoreductase expression and activity in a rat model of neuropathic pain

BACKGROUND: Koumine is an alkaloid monomer found abundantly in Gelsemium plants. It has been shown to reverse thermal hyperalgesia and mechanical allodynia induced by sciatic nerve chronic constriction injury (CCI) in rats in a dose-dependent manner. Interestingly, this effect is mediated by elevate...

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Detalles Bibliográficos
Autores principales: Qiu, Hong-Qiang, Xu, Ying, Jin, Gui-Lin, Yang, Jian, Liu, Ming, Li, Su-Ping, Yu, Chang-Xi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4529695/
https://www.ncbi.nlm.nih.gov/pubmed/26255228
http://dx.doi.org/10.1186/s12990-015-0050-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4529695/
https://www.ncbi.nlm.nih.gov/pubmed/26255228
http://dx.doi.org/10.1186/s12990-015-0050-1

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