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An in vivo morphometry study on the standard transsylvian trajectory for mesial temporal lobe epilepsy surgery

A safe and appropriate surgical approach to the medial temporal structure is a prerequisite to perform surgeries for temporal lobe epilepsy. We used in vivo morphometry to identify the standard direction for entry into the inferior horn of the lateral ventricle via the Sylvian fissure: an important...

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Autores principales: Hamasaki, Tadashi, Hirai, Toshinori, Yamada, Kazumichi, Kuratsu, Jun-ichi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4529845/
https://www.ncbi.nlm.nih.gov/pubmed/26266077
http://dx.doi.org/10.1186/s40064-015-1198-x
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author Hamasaki, Tadashi
Hirai, Toshinori
Yamada, Kazumichi
Kuratsu, Jun-ichi
author_facet Hamasaki, Tadashi
Hirai, Toshinori
Yamada, Kazumichi
Kuratsu, Jun-ichi
author_sort Hamasaki, Tadashi
collection PubMed
description A safe and appropriate surgical approach to the medial temporal structure is a prerequisite to perform surgeries for temporal lobe epilepsy. We used in vivo morphometry to identify the standard direction for entry into the inferior horn of the lateral ventricle via the Sylvian fissure: an important initial step in performing transsylvian selective amygdalohippocampectomy. 3D magnetic resonance images obtained from 28 patients without intra-parenchymal lesions were re-oriented to demonstrate all points in the Talairach space of the brain. The limen insulae and the midpoint between the hippocampal sulcus and the innominate sulcus on the coronal slice through the posterior edge of the amygdala were defined as the start and target points, respectively. We evaluated the direction of the vector between these two points and its validity in the brain of 12 patients with temporal lobe epilepsy. The direction of the mean approach vector was 52.4° posteriorly and 16.2° inferiorly. The mean approach vector on the axial plane showed the approximate parallelism with the sphenoid ridge in individual cases. The computer simulation revealed that our average approach vector correctly entered the inferior horn of the lateral ventricle in all temporal lobe epilepsy brains. In vivo morphometry may contribute to the further development of safe and minimally-invasive neurosurgical procedures. ELECTRONIC SUPPLEMENTARY MATERIAL: The online version of this article (doi:10.1186/s40064-015-1198-x) contains supplementary material, which is available to authorized users.
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spelling pubmed-45298452015-08-11 An in vivo morphometry study on the standard transsylvian trajectory for mesial temporal lobe epilepsy surgery Hamasaki, Tadashi Hirai, Toshinori Yamada, Kazumichi Kuratsu, Jun-ichi Springerplus Research A safe and appropriate surgical approach to the medial temporal structure is a prerequisite to perform surgeries for temporal lobe epilepsy. We used in vivo morphometry to identify the standard direction for entry into the inferior horn of the lateral ventricle via the Sylvian fissure: an important initial step in performing transsylvian selective amygdalohippocampectomy. 3D magnetic resonance images obtained from 28 patients without intra-parenchymal lesions were re-oriented to demonstrate all points in the Talairach space of the brain. The limen insulae and the midpoint between the hippocampal sulcus and the innominate sulcus on the coronal slice through the posterior edge of the amygdala were defined as the start and target points, respectively. We evaluated the direction of the vector between these two points and its validity in the brain of 12 patients with temporal lobe epilepsy. The direction of the mean approach vector was 52.4° posteriorly and 16.2° inferiorly. The mean approach vector on the axial plane showed the approximate parallelism with the sphenoid ridge in individual cases. The computer simulation revealed that our average approach vector correctly entered the inferior horn of the lateral ventricle in all temporal lobe epilepsy brains. In vivo morphometry may contribute to the further development of safe and minimally-invasive neurosurgical procedures. ELECTRONIC SUPPLEMENTARY MATERIAL: The online version of this article (doi:10.1186/s40064-015-1198-x) contains supplementary material, which is available to authorized users. Springer International Publishing 2015-08-09 /pmc/articles/PMC4529845/ /pubmed/26266077 http://dx.doi.org/10.1186/s40064-015-1198-x Text en © Hamasaki et al. 2015 Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made.
spellingShingle Research
Hamasaki, Tadashi
Hirai, Toshinori
Yamada, Kazumichi
Kuratsu, Jun-ichi
An in vivo morphometry study on the standard transsylvian trajectory for mesial temporal lobe epilepsy surgery
title An in vivo morphometry study on the standard transsylvian trajectory for mesial temporal lobe epilepsy surgery
title_full An in vivo morphometry study on the standard transsylvian trajectory for mesial temporal lobe epilepsy surgery
title_fullStr An in vivo morphometry study on the standard transsylvian trajectory for mesial temporal lobe epilepsy surgery
title_full_unstemmed An in vivo morphometry study on the standard transsylvian trajectory for mesial temporal lobe epilepsy surgery
title_short An in vivo morphometry study on the standard transsylvian trajectory for mesial temporal lobe epilepsy surgery
title_sort in vivo morphometry study on the standard transsylvian trajectory for mesial temporal lobe epilepsy surgery
topic Research
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4529845/
https://www.ncbi.nlm.nih.gov/pubmed/26266077
http://dx.doi.org/10.1186/s40064-015-1198-x
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