Cargando…

Unravelling the RNA-Binding Properties of SAFB Proteins in Breast Cancer Cells

Scaffold attachment factor B1 (SAFB1) and SAFB2 proteins are oestrogen (ER) corepressors that bind to and modulate ER activity through chromatin remodelling or interaction with the basal transcription machinery. SAFB proteins also have an internal RNA-recognition motif but little is known about the...

Descripción completa

Detalles Bibliográficos
Autores principales:	Hong, Elaine, Best, Andrew, Gautrey, Hannah, Chin, Jas, Razdan, Anshuli, Curk, Tomaz, Elliott, David J., Tyson-Capper, Alison J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi Publishing Corporation 2015
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4529905/ https://www.ncbi.nlm.nih.gov/pubmed/26273616 http://dx.doi.org/10.1155/2015/395816

Ejemplares similares

Clinical Significance of HER-2 Splice Variants in Breast Cancer Progression and Drug Resistance
por: Jackson, Claire, et al.
Publicado: (2013)

HER2 splice variants in breast cancer: investigating their impact on diagnosis and treatment outcomes
por: Hart, Vic, et al.
Publicado: (2020)

Regulation of Mcl-1 by SRSF1 and SRSF5 in Cancer Cells
por: Gautrey, Hannah L., et al.
Publicado: (2012)

iCLIP identifies novel roles for SAFB1 in regulating RNA processing and neuronal function
por: Rivers, Caroline, et al.
Publicado: (2015)

Scaffold attachment factor B2 (SAFB2)-null mice reveal non-redundant functions of SAFB2 compared with its paralog, SAFB1
por: Jiang, Shiming, et al.
Publicado: (2015)

No germline mutations in supposed tumour suppressor genes SAFB1 and SAFB2 in familial breast cancer with linkage to 19p
por: Bergman, Annika, et al.
Publicado: (2008)

HER2-PI9 and HER2-I12: two novel and functionally active splice variants of the oncogene HER2 in breast cancer
por: Hart, Vic, et al.
Publicado: (2021)

A monoclonal antibody raised against human EZH2 cross-reacts with the RNA-binding protein SAFB
por: Cherney, Rachel E., et al.
Publicado: (2023)

Role of MicroRNAs in Treatment Response in Prostate Cancer
por: Razdan, Anshuli, et al.
Publicado: (2018)

Inhibition of HSF1 and SAFB Granule Formation Enhances Apoptosis Induced by Heat Stress
por: Watanabe, Kazunori, et al.
Publicado: (2021)

Expression of Tra2β in Cancer Cells as a Potential Contributory Factor to Neoplasia and Metastasis
por: Best, Andrew, et al.
Publicado: (2013)

Short-term hypoxia triggers ROS and SAFB mediated nuclear matrix and mRNA splicing remodeling
por: Taze, Chrysa, et al.
Publicado: (2022)

Scaffold attachment factor B1 (SAFB1) heterozygosity does not influence Wnt-1 or DMBA-induced tumorigenesis
por: Kaipparettu, Benny Abraham, et al.
Publicado: (2009)

Human Tra2 proteins jointly control a CHEK1 splicing switch among alternative and constitutive target exons
por: Best, Andrew, et al.
Publicado: (2014)

Alternative splicing and the progesterone receptor in breast cancer
por: Cork, David MW, et al.
Publicado: (2008)

The chromatin scaffold protein SAFB1 localizes SUMO-1 to the promoters of ribosomal protein genes to facilitate transcription initiation and splicing
por: Liu, Hui-wen, et al.
Publicado: (2015)

FUS interacts with nuclear matrix-associated protein SAFB1 as well as Matrin3 to regulate splicing and ligand-mediated transcription
por: Yamaguchi, Atsushi, et al.
Publicado: (2016)

Alternative splicing: an important mechanism for myometrial gene regulation that can be manipulated to target specific genes associated with preterm labour
por: Tyson-Capper, Alison Jane
Publicado: (2007)

Orthogonal matrix factorization enables integrative analysis of multiple RNA binding proteins
por: Stražar, Martin, et al.
Publicado: (2016)

SKA1 promotes tumor metastasis via SAFB-mediated transcription repression of DUSP6 in clear cell renal cell carcinoma
por: Pu, Yan, et al.
Publicado: (2022)

The Scaffold attachment factor b1 (Safb1) regulates myogenic differentiation by facilitating the transition of myogenic gene chromatin from a repressed to an activated state
por: Hernández-Hernández, J. Manuel, et al.
Publicado: (2013)

FASTKD2 is an RNA-binding protein required for mitochondrial RNA processing and translation
por: Popow, Johannes, et al.
Publicado: (2015)

The RNA-binding landscapes of two SR proteins reveal unique functions and binding to diverse RNA classes
por: Änkö, Minna-Liisa, et al.
Publicado: (2012)

SNPsyn: detection and exploration of SNP–SNP interactions
por: Curk, Tomaz, et al.
Publicado: (2011)

Binding site density enables paralog-specific activity of SLM2 and Sam68 proteins in Neurexin2 AS4 splicing control
por: Danilenko, Marina, et al.
Publicado: (2017)

Promiscuous RNA Binding Ensures Effective Encapsidation of APOBEC3 Proteins by HIV-1
por: Apolonia, Luis, et al.
Publicado: (2015)

Comprehensive Identification of RNA-Binding Domains in Human Cells
por: Castello, Alfredo, et al.
Publicado: (2016)

Does replication groups scoring reduce false positive rate in SNP interaction discovery?
por: Toplak, Marko, et al.
Publicado: (2010)

Heterogeneous computing architecture for fast detection of SNP-SNP interactions
por: Sluga, Davor, et al.
Publicado: (2014)

Sparse data embedding and prediction by tropical matrix factorization
por: Omanović, Amra, et al.
Publicado: (2021)

Inflammatory Signalling in Fetal Membranes: Increased Expression Levels of TLR 1 in the Presence of Preterm Histological Chorioamnionitis
por: Waring, Gareth J., et al.
Publicado: (2015)

An ancient germ cell-specific RNA-binding protein protects the germline from cryptic splice site poisoning
por: Ehrmann, Ingrid, et al.
Publicado: (2019)

Yeast as a cell factory: current state and perspectives
por: Kavšček, Martin, et al.
Publicado: (2015)

SIMBA Method—Simultaneous Detection of Antimicrobial and Anti-biofilm Activity of New Compounds Using Salmonella Infantis
por: Sterniša, Meta, et al.
Publicado: (2023)

Social Work in a Military Hospital
por: Gautrey, Subaltern B.
Publicado: (1946)

Unraveling the Impact of Cysteine-to-Serine Mutations on the Structural and Functional Properties of Cu(I)-Binding Proteins
por: Pavlin, Matic, et al.
Publicado: (2019)

Inflammatory responses to metal oxide ceramic nanopowders
por: Jamieson, Shannon, et al.
Publicado: (2021)

Unraveling determinants of transcription factor binding outside the core binding site
por: Levo, Michal, et al.
Publicado: (2015)

The RNA-binding proteomes from yeast to man harbour conserved enigmRBPs
por: Beckmann, Benedikt M., et al.
Publicado: (2015)

Improved binding site assignment by high-resolution mapping of RNA–protein interactions using iCLIP
por: Hauer, Christian, et al.
Publicado: (2015)

Cannot write session to /tmp/vufind_sessions/sess_o88ajbadmm2i9jrsq1brdlrork