Translational Control Protein 80 Stimulates IRES-Mediated Translation of p53 mRNA in Response to DNA Damage

Synthesis of the p53 tumor suppressor increases following DNA damage. This increase and subsequent activation of p53 are essential for the protection of normal cells against tumorigenesis. We previously discovered an internal ribosome entry site (IRES) that is located at the 5′-untranslated region (...

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Detalles Bibliográficos
Autores principales: Halaby, Marie-Jo, Li, Yan, Harris, Benjamin R., Jiang, Shuxia, Miskimins, W. Keith, Cleary, Margot P., Yang, Da-Qing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4529924/
https://www.ncbi.nlm.nih.gov/pubmed/26273641
http://dx.doi.org/10.1155/2015/708158

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