Allium cepa L. and Quercetin Inhibit RANKL/Porphyromonas gingivalis LPS-Induced Osteoclastogenesis by Downregulating NF-κB Signaling Pathway

Objectives. We evaluated the in vitro modulatory effects of Allium cepa L. extract (AcE) and quercetin (Qt) on osteoclastogenesis under inflammatory conditions (LPS-induced). Methods. RAW 264.7 cells were differentiated with 30 ng/mL of RANKL, costimulated with PgLPS (1 µg/mL), and treated with AcE...

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Detalles Bibliográficos
Autores principales: Oliveira, Tatiane, Figueiredo, Camila A., Brito, Carlos, Stavroullakis, Alexander, Ferreira, Ana Carolina, Nogueira-Filho, Getulio, Prakki, Anuradha
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4529940/
https://www.ncbi.nlm.nih.gov/pubmed/26273314
http://dx.doi.org/10.1155/2015/704781

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