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Mitochondrial SOD2 regulates epithelial-mesenchymal transition and cell populations defined by differential CD44 expression

Epithelial-mesenchymal transition (EMT) promotes cancer cell invasion, metastasis and treatment failure. EMT may be activated in cancer cells by reactive oxygen species (ROS). EMT may promote conversion of a subset of cancer cells from a CD44(Low)-CD24(High) (CD44L) epithelial phenotype to a CD44(Hi...

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Detalles Bibliográficos
Autores principales:	Kinugasa, Hideaki, Whelan, Kelly A., Tanaka, Koji, Natsuizaka, Mitsuteru, Long, Apple, Guo, Andy, Chang, Sanders, Kagawa, Shingo, Srinivasan, Satish, Guha, Manti, Yamamoto, Kazuhide, St. Clair, Daret K., Avadhani, Narayan G., Diehl, J. Alan, Nakagawa, Hiroshi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	2015
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4530096/ https://www.ncbi.nlm.nih.gov/pubmed/25659582 http://dx.doi.org/10.1038/onc.2014.449

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