Effects of Physiological and Synthetic IAP Antagonism on c-IAP-Dependent Signaling

Cellular inhibitor of apoptosis proteins 1 and 2 (c-IAP1/2) play central roles in signal transduction mediated by numerous receptors that participate in inflammatory and immune responses. In certain pathways, such as activation of NF-κB, their degradation is a major regulatory event and is physiolog...

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Detalles Bibliográficos
Autores principales: Kocab, Andrew J., Veloso, Artur, Paulsen, Michelle T., Ljungman, Mats, Duckett, Colin S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4530109/
https://www.ncbi.nlm.nih.gov/pubmed/25659587
http://dx.doi.org/10.1038/onc.2015.3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4530109/
https://www.ncbi.nlm.nih.gov/pubmed/25659587
http://dx.doi.org/10.1038/onc.2015.3

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