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Effects of Physiological and Synthetic IAP Antagonism on c-IAP-Dependent Signaling
Cellular inhibitor of apoptosis proteins 1 and 2 (c-IAP1/2) play central roles in signal transduction mediated by numerous receptors that participate in inflammatory and immune responses. In certain pathways, such as activation of NF-κB, their degradation is a major regulatory event and is physiolog...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
2015
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4530109/ https://www.ncbi.nlm.nih.gov/pubmed/25659587 http://dx.doi.org/10.1038/onc.2015.3 |