Cargando…

CD4 changes among virologically suppressed patients on antiretroviral therapy: a systematic review and meta-analysis

INTRODUCTION: The effectiveness of antiretroviral therapy (ART) is assessed by measuring CD4 cell counts and viral load. Recent studies have questioned the added value of routine CD4 cell count measures in patients who are virologically suppressed. METHODS: We systematically searched three databases...

Descripción completa

Detalles Bibliográficos
Autores principales:	Ford, Nathan, Stinson, Kathryn, Gale, Howard, Mills, Edward J, Stevens, Wendy, González, Mercedes P, Markby, Jessica, Hill, Andrew
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	International AIDS Society 2015
Materias:	Review Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4530137/ https://www.ncbi.nlm.nih.gov/pubmed/26257204 http://dx.doi.org/10.7448/IAS.18.1.20061

Ejemplares similares

Early Adherence to Antiretroviral Medication as a Predictor of Long-Term HIV Virological Suppression: Five-Year Follow Up of an Observational Cohort
por: Ford, Nathan, et al.
Publicado: (2010)

POC CD4 Testing Improves Linkage to HIV Care and Timeliness of ART Initiation in a Public Health Approach: A Systematic Review and Meta-Analysis
por: Vojnov, Lara, et al.
Publicado: (2016)

Modifying Antiretroviral Therapy in Virologically Suppressed HIV-1-Infected Patients
por: Collins, Sean E., et al.
Publicado: (2015)

Assessment of metabolic and mitochondrial dynamics in CD4+ and CD8+ T cells in virologically suppressed HIV-positive individuals on combination antiretroviral therapy
por: Masson, Jesse J. R., et al.
Publicado: (2017)

The first decade of antiretroviral therapy in Africa
por: Ford, Nathan, et al.
Publicado: (2011)

Adherence to Antiretroviral Therapy and Virologic Failure: A Meta-Analysis
por: Bezabhe, Woldesellassie M., et al.
Publicado: (2016)

Determinants of Restoration of CD4 and CD8 Cell Counts and Their Ratio in HIV-1–Positive Individuals With Sustained Virological Suppression on Antiretroviral Therapy
por: Gras, Luuk, et al.
Publicado: (2019)

CD4 rate of increase is preferred to CD4 threshold for predicting outcomes among virologically suppressed HIV-infected adults on antiretroviral therapy
por: Aldrete, Sol, et al.
Publicado: (2020)

Immunological failure despite virological suppression in HIV seropositive individuals on antiretroviral therapy
por: Prabhakar, B., et al.
Publicado: (2011)

Association of Suboptimal Antiretroviral Therapy Adherence With Inflammation in Virologically Suppressed Individuals Enrolled in the SMART Study
por: Castillo-Mancilla, Jose R, et al.
Publicado: (2017)

Predictors of suboptimal CD4 response among women achieving virologic suppression in a randomized antiretroviral treatment trial, Africa
por: Asmelash, Aida, et al.
Publicado: (2014)

Antiretroviral adherence and virologic suppression in partnered and unpartnered HIV-positive individuals in southern Brazil
por: de Melo, Marineide Gonçalves, et al.
Publicado: (2019)

Virological suppression in children and adolescents is not influenced by genotyping, but depends on optimal adherence to antiretroviral therapy
por: Abreu, Juliana Costa de, et al.
Publicado: (2017)

Can we stop AIDS with antiretroviral-based treatment as prevention?
por: Mills, Edward J, et al.
Publicado: (2013)

Virologic suppression in response to antiretroviral therapy despite extensive resistance within HIV-1 reverse transcriptase after the first virologic failure
por: Oliveira, Marta Iglis, et al.
Publicado: (2018)

Gender differences in clinical, immunological, and virological outcomes in highly active antiretroviral-treated HIV–HCV coinfected patients
por: Emery, Joel, et al.
Publicado: (2010)

Factors affecting antiretroviral pharmacokinetics in HIV-infected women with virologic suppression on combination antiretroviral therapy: a cross-sectional study
por: Loutfy, Mona Rafik, et al.
Publicado: (2013)

Editorial Commentary: Immunodeficiency at Start of Antiretroviral Therapy: The Persistent Problem of Late Presentation to Care
por: Ford, Nathan, et al.
Publicado: (2015)

Persistent disparities in antiretroviral treatment (ART) coverage and virological suppression across Europe, 2004 to 2015
por: Laut, Kamilla, et al.
Publicado: (2018)

Efficacy and safety of switching from branded to generic antiretrovirals in virologically suppressed HIV-infected patients
por: Gianotti, Nicola, et al.
Publicado: (2017)

Immunological status and virological suppression among HIV-infected adults on highly active antiretroviral therapy
por: Melku, Mulugeta, et al.
Publicado: (2020)

Combination anti‐HIV antibodies to achieve antiretroviral therapy‐free virological suppression in infected individuals
por: Rai, M. Ali, et al.
Publicado: (2022)

Beyond Undetectable: Modeling the Clinical Benefit of Improved Antiretroviral Adherence in Persons With Human Immunodeficiency Virus With Virologic Suppression
por: Castillo-Mancilla, Jose R, et al.
Publicado: (2023)

Use of peers to improve adherence to antiretroviral therapy: a global network meta-analysis
por: Kanters, Steve, et al.
Publicado: (2016)

Conditional Cash Transfers to Increase Retention in PMTCT Care, Antiretroviral Adherence, and Postpartum Virological Suppression: A Randomized Controlled Trial
por: Yotebieng, Marcel, et al.
Publicado: (2016)

Rates of Initial Virological Suppression and Subsequent Virological Failure After Initiating Highly Active Antiretroviral Therapy: The Impact of Aboriginal Ethnicity and Injection Drug Use
por: Martin, L.J., et al.
Publicado: (2010)

Early Mortality and AIDS Progression Despite High Initial Antiretroviral Therapy Adherence and Virologic Suppression in Botswana
por: Steele, Katherine T., et al.
Publicado: (2011)

The Risk of Virologic Failure Decreases with Duration of HIV Suppression, at Greater than 50% Adherence to Antiretroviral Therapy
por: Rosenblum, Michael, et al.
Publicado: (2009)

Durable Suppression of HIV-1 after Virologic Monitoring-Based Antiretroviral Adherence Counseling in Rakai, Uganda
por: Billioux, Alexander, et al.
Publicado: (2015)

Discordant CSF/plasma HIV-1 RNA in individuals on virologically suppressive antiretroviral therapy in Western India
por: Dravid, Ameet N., et al.
Publicado: (2018)

978. Changes in BMI Associated with Antiretroviral Regimens in Treatment-Experienced, Virologically Suppressed Individuals Living with HIV
por: Mounzer, Karam, et al.
Publicado: (2019)

Socio-economic condition and lack of virological suppression among adults and adolescents receiving antiretroviral therapy in Ethiopia
por: Plymoth, Martin, et al.
Publicado: (2020)

Predictors of Virological Failure and Time to Viral Suppression of First-Line Integrase Inhibitor–Based Antiretroviral Treatment
por: Pyngottu, Ashima, et al.
Publicado: (2020)

Drug resistance in HIV patients with virological failure or slow virological response to antiretroviral therapy in Ethiopia
por: Abdissa, Alemseged, et al.
Publicado: (2014)

Pregnancy and Virologic Response to Antiretroviral Therapy in South Africa
por: Westreich, Daniel, et al.
Publicado: (2011)

Virological Response and Antiretroviral Drug Resistance Emerging during Antiretroviral Therapy at Three Treatment Centers in Uganda
por: Kaleebu, Pontiano, et al.
Publicado: (2015)

Virological failure and development of new resistance mutations according to CD4 count at combination antiretroviral therapy initiation
por: Jose, S, et al.
Publicado: (2015)

Performance of non-laboratory staff for diagnostic testing and specimen collection in HIV programs: A systematic review and meta-analysis
por: Vojnov, Lara, et al.
Publicado: (2019)

Quantitative Assessment of Intra-Patient Variation in CD4+ T Cell Counts in Stable, Virologically-Suppressed, HIV-Infected Subjects
por: Gordon, Claire L., et al.
Publicado: (2015)

Viral suppression in adults, adolescents and children receiving antiretroviral therapy in Cameroon: adolescents at high risk of virological failure in the era of “test and treat”
por: Fokam, Joseph, et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_avkqgpj6jk48l743trenfihvsc