Cargando…
A pain-mediated neural signal induces relapse in murine autoimmune encephalomyelitis, a multiple sclerosis model
Although pain is a common symptom of various diseases and disorders, its contribution to disease pathogenesis is not well understood. Here we show using murine experimental autoimmune encephalomyelitis (EAE), a model for multiple sclerosis (MS), that pain induces EAE relapse. Mechanistic analysis sh...
Autores principales: | Arima, Yasunobu, Kamimura, Daisuke, Atsumi, Toru, Harada, Masaya, Kawamoto, Tadafumi, Nishikawa, Naoki, Stofkova, Andrea, Ohki, Takuto, Higuchi, Kotaro, Morimoto, Yuji, Wieghofer, Peter, Okada, Yuka, Mori, Yuki, Sakoda, Saburo, Saika, Shizuya, Yoshioka, Yoshichika, Komuro, Issei, Yamashita, Toshihide, Hirano, Toshio, Prinz, Marco, Murakami, Masaaki |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
eLife Sciences Publications, Ltd
2015
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4530187/ https://www.ncbi.nlm.nih.gov/pubmed/26193120 http://dx.doi.org/10.7554/eLife.08733 |
Ejemplares similares
-
Brain micro-inflammation at specific vessels dysregulates organ-homeostasis via the activation of a new neural circuit
por: Arima, Yasunobu, et al.
Publicado: (2017) -
Photopic light-mediated down-regulation of local α(1A)-adrenergic signaling protects blood-retina barrier in experimental autoimmune uveoretinitis
por: Stofkova, Andrea, et al.
Publicado: (2019) -
Naïve T Cell Homeostasis Regulated by Stress Responses and TCR Signaling
por: Kamimura, Daisuke, et al.
Publicado: (2015) -
Regulation of Immune Cell Infiltration into the CNS by Regional Neural Inputs Explained by the Gate Theory
por: Arima, Yasunobu, et al.
Publicado: (2013) -
KDEL receptor 1 regulates T-cell homeostasis via PP1 that is a key phosphatase for ISR
por: Kamimura, Daisuke, et al.
Publicado: (2015)