KRAS and CREBBP mutations: a relapse-linked malicious liaison in childhood high hyperdiploid acute lymphoblastic leukemia

High hyperdiploidy defines the largest genetic entity of childhood acute lymphoblastic leukemia (ALL). Despite its relatively low recurrence risk, this subgroup generates a high proportion of relapses. The cause and origin of these relapses remains obscure. We therefore explored the mutational lands...

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Detalles Bibliográficos
Autores principales: Malinowska-Ozdowy, K, Frech, C, Schönegger, A, Eckert, C, Cazzaniga, G, Stanulla, M, zur Stadt, U, Mecklenbräuker, A, Schuster, M, Kneidinger, D, von Stackelberg, A, Locatelli, F, Schrappe, M, Horstmann, M A, Attarbaschi, A, Bock, C, Mann, G, Haas, O A, Panzer-Grümayer, R
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4530204/
https://www.ncbi.nlm.nih.gov/pubmed/25917266
http://dx.doi.org/10.1038/leu.2015.107

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