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Association of Metabolic Syndrome with the Cardioankle Vascular Index in Asymptomatic Korean Population

Aim. Metabolic syndrome is characterized by a cluster of atherosclerotic cardiovascular risk factors. The cardioankle vascular index (CAVI) reflects arterial stiffness and may be used as an indicator of atherosclerotic cardiovascular disease. In this study, we investigated the association of CAVI wi...

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Autores principales: Nam, Su-Hyun, Kang, Sung-Goo, Lee, Yun-Ah, Song, Sang-Wook, Rho, Jun-Seung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4530251/
https://www.ncbi.nlm.nih.gov/pubmed/26273666
http://dx.doi.org/10.1155/2015/328585
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author Nam, Su-Hyun
Kang, Sung-Goo
Lee, Yun-Ah
Song, Sang-Wook
Rho, Jun-Seung
author_facet Nam, Su-Hyun
Kang, Sung-Goo
Lee, Yun-Ah
Song, Sang-Wook
Rho, Jun-Seung
author_sort Nam, Su-Hyun
collection PubMed
description Aim. Metabolic syndrome is characterized by a cluster of atherosclerotic cardiovascular risk factors. The cardioankle vascular index (CAVI) reflects arterial stiffness and may be used as an indicator of atherosclerotic cardiovascular disease. In this study, we investigated the association of CAVI with metabolic syndrome. Methods. A total of 1,144 adults were included in this study. We measured CAVIs and examined blood samples to identify metabolic syndrome according to WHO Asia Pacific criteria and NCEP-ATPIII criteria. AST, ALT, r-GTP, BUN, creatinine, high sensitivity C-reactive protein, and uric acid were also measured. Results. CAVI values were significantly higher in subjects with metabolic syndrome than those without metabolic syndrome and increased according to the number of metabolic syndrome components present. Subjects with high fasting blood sugar levels or high blood pressure showed high CAVI values. Multiple regression analysis showed that age, sex, diastolic blood pressure, and uric acid were independent predictors of CAVI. Conclusion. Subjects with metabolic syndrome had high CAVIs, which indicated arterial stiffness, and were closely associated with an increase in the number of metabolic risk factors. The individual risk factors for metabolic syndrome have the synergistic effect of elevating arterial stiffness in asymptomatic Korean population.
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spelling pubmed-45302512015-08-13 Association of Metabolic Syndrome with the Cardioankle Vascular Index in Asymptomatic Korean Population Nam, Su-Hyun Kang, Sung-Goo Lee, Yun-Ah Song, Sang-Wook Rho, Jun-Seung J Diabetes Res Research Article Aim. Metabolic syndrome is characterized by a cluster of atherosclerotic cardiovascular risk factors. The cardioankle vascular index (CAVI) reflects arterial stiffness and may be used as an indicator of atherosclerotic cardiovascular disease. In this study, we investigated the association of CAVI with metabolic syndrome. Methods. A total of 1,144 adults were included in this study. We measured CAVIs and examined blood samples to identify metabolic syndrome according to WHO Asia Pacific criteria and NCEP-ATPIII criteria. AST, ALT, r-GTP, BUN, creatinine, high sensitivity C-reactive protein, and uric acid were also measured. Results. CAVI values were significantly higher in subjects with metabolic syndrome than those without metabolic syndrome and increased according to the number of metabolic syndrome components present. Subjects with high fasting blood sugar levels or high blood pressure showed high CAVI values. Multiple regression analysis showed that age, sex, diastolic blood pressure, and uric acid were independent predictors of CAVI. Conclusion. Subjects with metabolic syndrome had high CAVIs, which indicated arterial stiffness, and were closely associated with an increase in the number of metabolic risk factors. The individual risk factors for metabolic syndrome have the synergistic effect of elevating arterial stiffness in asymptomatic Korean population. Hindawi Publishing Corporation 2015 2015-07-27 /pmc/articles/PMC4530251/ /pubmed/26273666 http://dx.doi.org/10.1155/2015/328585 Text en Copyright © 2015 Su-Hyun Nam et al. https://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Research Article
Nam, Su-Hyun
Kang, Sung-Goo
Lee, Yun-Ah
Song, Sang-Wook
Rho, Jun-Seung
Association of Metabolic Syndrome with the Cardioankle Vascular Index in Asymptomatic Korean Population
title Association of Metabolic Syndrome with the Cardioankle Vascular Index in Asymptomatic Korean Population
title_full Association of Metabolic Syndrome with the Cardioankle Vascular Index in Asymptomatic Korean Population
title_fullStr Association of Metabolic Syndrome with the Cardioankle Vascular Index in Asymptomatic Korean Population
title_full_unstemmed Association of Metabolic Syndrome with the Cardioankle Vascular Index in Asymptomatic Korean Population
title_short Association of Metabolic Syndrome with the Cardioankle Vascular Index in Asymptomatic Korean Population
title_sort association of metabolic syndrome with the cardioankle vascular index in asymptomatic korean population
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4530251/
https://www.ncbi.nlm.nih.gov/pubmed/26273666
http://dx.doi.org/10.1155/2015/328585
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