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Histone Deacetylase Inhibitor Trichostatin A Ameliorated Endotoxin-Induced Neuroinflammation and Cognitive Dysfunction
Excessive production of cytokines by microglia may cause cognitive dysfunction and long-lasting behavioral changes. Activating the peripheral innate immune system stimulates cytokine secretion in the central nervous system, which modulates cognitive function. Histone deacetylases (HDACs) modulate cy...
Autores principales: | Hsing, Chung-Hsi, Hung, Shih-Kai, Chen, Yeong-Chang, Wei, Tsui-Shan, Sun, Ding-Ping, Wang, Jhi-Joung, Yeh, Ching-Hua |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi Publishing Corporation
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4530275/ https://www.ncbi.nlm.nih.gov/pubmed/26273133 http://dx.doi.org/10.1155/2015/163140 |
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