MicroRNA-9 induces defective trafficking of Nav1.1 and Nav1.2 by targeting Navβ2 protein coding region in rat with chronic brain hypoperfusion

BACKGROUND: Previous studies have demonstrated that the trafficking defects of Nav1.1/Nav1.2 are involved in the dementia pathophysiology. However, the detailed mechanisms are not fully understood. Moreover, whether the impaired miRNAs regulation linked to dementia is a key player in sodium channel...

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Detalles Bibliográficos
Autores principales: Sun, Li-Hua, Yan, Mei-Ling, Hu, Xue-Ling, Peng, Li-Wei, Che, Hui, Bao, Ya-Nan, Guo, Fei, Liu, Tong, Chen, Xin, Zhang, Rong, Ban, Tao, Wang, Ning, Liu, Huai-Lei, Hou, Xu, Ai, Jing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4530481/
https://www.ncbi.nlm.nih.gov/pubmed/26259688
http://dx.doi.org/10.1186/s13024-015-0032-9

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