Fanconi anemia: young patients at high risk for squamous cell carcinoma

BACKGROUND: Fanconi anemia is one of the best studied inherited cancer-prone diseases. Greatly improved protocols for hematopoietic stem cell transplantation increasingly save the lives of these young patients. However, in both transplanted and not transplanted patients, the emergence of aggressive...

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Detalles Bibliográficos
Autores principales: Velleuer, Eunike, Dietrich, Ralf
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2014
Materias:
Mini Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4530570/
https://www.ncbi.nlm.nih.gov/pubmed/26567103
http://dx.doi.org/10.1186/s40348-014-0009-8
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author Velleuer, Eunike
Dietrich, Ralf
author_facet Velleuer, Eunike
Dietrich, Ralf
author_sort Velleuer, Eunike
collection PubMed
description BACKGROUND: Fanconi anemia is one of the best studied inherited cancer-prone diseases. Greatly improved protocols for hematopoietic stem cell transplantation increasingly save the lives of these young patients. However, in both transplanted and not transplanted patients, the emergence of aggressive squamous cell carcinoma represents a major medical challenge. CONCLUSIONS: This mini review summarizes current knowledge about the pathogenesis of squamous cell carcinoma (SCC) in the special context of Fanconi anemia.
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spelling pubmed-45305702015-08-19 Fanconi anemia: young patients at high risk for squamous cell carcinoma Velleuer, Eunike Dietrich, Ralf Mol Cell Pediatr Mini Review BACKGROUND: Fanconi anemia is one of the best studied inherited cancer-prone diseases. Greatly improved protocols for hematopoietic stem cell transplantation increasingly save the lives of these young patients. However, in both transplanted and not transplanted patients, the emergence of aggressive squamous cell carcinoma represents a major medical challenge. CONCLUSIONS: This mini review summarizes current knowledge about the pathogenesis of squamous cell carcinoma (SCC) in the special context of Fanconi anemia. Springer Berlin Heidelberg 2014-11-01 /pmc/articles/PMC4530570/ /pubmed/26567103 http://dx.doi.org/10.1186/s40348-014-0009-8 Text en © Velleuer and Dietrich ; Licensee Springer 2014 This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited.
spellingShingle Mini Review
Velleuer, Eunike
Dietrich, Ralf
Fanconi anemia: young patients at high risk for squamous cell carcinoma
title Fanconi anemia: young patients at high risk for squamous cell carcinoma
title_full Fanconi anemia: young patients at high risk for squamous cell carcinoma
title_fullStr Fanconi anemia: young patients at high risk for squamous cell carcinoma
title_full_unstemmed Fanconi anemia: young patients at high risk for squamous cell carcinoma
title_short Fanconi anemia: young patients at high risk for squamous cell carcinoma
title_sort fanconi anemia: young patients at high risk for squamous cell carcinoma
topic Mini Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4530570/
https://www.ncbi.nlm.nih.gov/pubmed/26567103
http://dx.doi.org/10.1186/s40348-014-0009-8
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