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Matrix metalloproteinases and epileptogenesis
Matrix metalloproteinases are vital drivers of synaptic remodeling in health and disease. It is suggested that at early stages of epileptogenesis, inhibition of matrix metalloproteinases may help ameliorate cell death, aberrant network rewiring, and neuroinflammation and prevent development of epile...
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Berlin Heidelberg
2014
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4530574/ https://www.ncbi.nlm.nih.gov/pubmed/26567100 http://dx.doi.org/10.1186/s40348-014-0006-y |
Sumario: | Matrix metalloproteinases are vital drivers of synaptic remodeling in health and disease. It is suggested that at early stages of epileptogenesis, inhibition of matrix metalloproteinases may help ameliorate cell death, aberrant network rewiring, and neuroinflammation and prevent development of epilepsy. |
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