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Reduced density of glutamine synthetase immunoreactive astrocytes in different cortical areas in major depression but not in bipolar I disorder

There is increasing evidence for disturbances within the glutamate system in patients with affective disorders, which involve disruptions of the glutamate–glutamine-cycle. The mainly astroglia-located enzyme glutamine synthetase (GS) catalyzes the ATP-dependent condensation of ammonia and glutamate...

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Detalles Bibliográficos
Autores principales:	Bernstein, Hans-Gert, Meyer-Lotz, Gabriela, Dobrowolny, Henrik, Bannier, Jana, Steiner, Johann, Walter, Martin, Bogerts, Bernhard
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2015
Materias:	Neuroscience
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4530620/ https://www.ncbi.nlm.nih.gov/pubmed/26321908 http://dx.doi.org/10.3389/fncel.2015.00273

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