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CD73 Activity is Dispensable for the Polarization of M2 Macrophages

The ectoenzyme CD73 catalyzes the hydrolysis of AMP, and is one of the most important producers of extracellular adenosine. On regulatory T cells, CD73 is necessary for immunosuppressive functions, and on Th17 cells CD73-generated adenosine exerts anti-inflammatory effects. However, the expression a...

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Detalles Bibliográficos
Autores principales:	Eichin, Dominik, Laurila, Juha P., Jalkanen, Sirpa, Salmi, Marko
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2015
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4530872/ https://www.ncbi.nlm.nih.gov/pubmed/26258883 http://dx.doi.org/10.1371/journal.pone.0134721

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