Islet Oxygen Consumption Rate (OCR) Dose Predicts Insulin Independence in Clinical Islet Autotransplantation

BACKGROUND: Reliable in vitro islet quality assessment assays that can be performed routinely, prospectively, and are able to predict clinical transplant outcomes are needed. In this paper we present data on the utility of an assay based on cellular oxygen consumption rate (OCR) in predicting clinic...

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Detalles Bibliográficos
Autores principales: Papas, Klearchos K., Bellin, Melena D., Sutherland, David E. R., Suszynski, Thomas M., Kitzmann, Jennifer P., Avgoustiniatos, Efstathios S., Gruessner, Angelika C., Mueller, Kathryn R., Beilman, Gregory J., Balamurugan, Appakalai N., Loganathan, Gopalakrishnan, Colton, Clark K., Koulmanda, Maria, Weir, Gordon C., Wilhelm, Josh J., Qian, Dajun, Niland, Joyce C., Hering, Bernhard J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4530873/
https://www.ncbi.nlm.nih.gov/pubmed/26258815
http://dx.doi.org/10.1371/journal.pone.0134428

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