Cargando…

Celastrol induces apoptosis of human osteosarcoma cells via the mitochondrial apoptotic pathway

Celastrol is an active compound extracted from the root bark of Triptergium wilfordii Hook F., also known as 'Thunder of God Vine'. It is a well-known Chinese medicinal herb that was found to inhibit tumor cell growth and promote apoptosis in several tumor cell lines. However, research int...

Descripción completa

Detalles Bibliográficos
Autores principales:	YU, XIAOLONG, ZHOU, XIN, FU, CHANGLIN, WANG, QIANG, NIE, TAO, ZOU, FAN, GUO, RUNSHENG, LIU, HUCHENG, ZHANG, BIN, DAI, MIN
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	D.A. Spandidos 2015
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4530898/ https://www.ncbi.nlm.nih.gov/pubmed/26165547 http://dx.doi.org/10.3892/or.2015.4124

Ejemplares similares

Efficacy of celastrol combined with cisplatin in enhancing the apoptosis of U-2OS osteosarcoma cells via the mitochondrial and endoplasmic reticulum pathways of apoptosis
por: Wang, Qiang, et al.
Publicado: (2019)

Triggering of Apoptosis in Osteosarcoma 143B Cell Line by Carbon Quantum Dots via the Mitochondrial Apoptotic Signal Pathway
por: Jiao, Yang, et al.
Publicado: (2020)

Celastrol Inhibits Canine Mammary Tumor Cells by Inducing Apoptosis via the Caspase Pathway
por: Ou, Guoxing, et al.
Publicado: (2022)

Celastrol induces apoptosis and autophagy via the ROS/JNK signaling pathway in human osteosarcoma cells: an in vitro and in vivo study
por: Li, H-Y, et al.
Publicado: (2015)

Toosendanin induces the apoptosis of human Ewing's sarcoma cells via the mitochondrial apoptotic pathway
por: Gao, Tian, et al.
Publicado: (2019)

Calycosin induces apoptosis via p38-MAPK pathway-mediated activation of the mitochondrial apoptotic pathway in human osteosarcoma 143B cells
por: Tian, Wei, et al.
Publicado: (2020)

Regulating mitochondrial homeostasis and inhibiting inflammatory responses through Celastrol
por: Tao, Zhenyu, et al.
Publicado: (2022)

Celastrol inhibits gastric cancer growth by induction of apoptosis and autophagy
por: Lee, Hyun-Woo, et al.
Publicado: (2014)

Lumbar spinal canal osteosarcoma: A case report
por: Chen, De-jian, et al.
Publicado: (2018)

PNS-R1 inhibits Dex-induced bronchial epithelial cells apoptosis in asthma through mitochondrial apoptotic pathway
por: Zou, Wenjing, et al.
Publicado: (2019)

The genome of Tripterygium wilfordii and characterization of the celastrol biosynthesis pathway
por: Pei, Tianlin, et al.
Publicado: (2021)

Celastrol slows the progression of early diabetic nephropathy in rats via the PI3K/AKT pathway
por: Nie, Yusong, et al.
Publicado: (2020)

Systematic identification of Celastrol-binding proteins reveals that Shoc2 is inhibited by Celastrol
por: Xiao-pei, Huang, et al.
Publicado: (2018)

Cadmium-induced apoptosis in neuronal cells is mediated by Fas/FasL-mediated mitochondrial apoptotic signaling pathway
por: Yuan, Yan, et al.
Publicado: (2018)

Beclin-1 knockdown decreases proliferation, invasion and migration of Ewing sarcoma SK-ES-1 cells via inhibition of MMP-9
por: Ye, Conglin, et al.
Publicado: (2021)

Celastrol increases osteosarcoma cell lysis by γδ T cells through up-regulation of death receptors
por: Li, Zhaoxu, et al.
Publicado: (2016)

Identification of a Conserved Anti-Apoptotic Protein That Modulates the Mitochondrial Apoptosis Pathway
por: Zhang, Yu, et al.
Publicado: (2011)

Natural Proteasome Inhibitor Celastrol Suppresses Androgen-Independent Prostate Cancer Progression by Modulating Apoptotic Proteins and NF-kappaB
por: Dai, Yao, et al.
Publicado: (2010)

Regulation of Intrinsic and Extrinsic Apoptotic Pathways in Osteosarcoma Cells Following Oleandrin Treatment
por: Ma, Yunlong, et al.
Publicado: (2016)

TAZ promotes cell growth and inhibits Celastrol-induced cell apoptosis
por: Wang, Shuren, et al.
Publicado: (2016)

Induction of Apoptosis in HeLa Cells by a Novel Peptide from Fruiting Bodies of Morchella importuna via the Mitochondrial Apoptotic Pathway
por: Xiong, Chuan, et al.
Publicado: (2021)

HSP27 Inhibits Homocysteine-Induced Endothelial Apoptosis by Modulation of ROS Production and Mitochondrial Caspase-Dependent Apoptotic Pathway
por: Tian, Xin, et al.
Publicado: (2016)

Direct inhibition of c-Myc-Max heterodimers by celastrol and celastrol-inspired triterpenoids
por: Wang, Huabo, et al.
Publicado: (2015)

Dodecyl gallate induces apoptosis by upregulating the caspase-dependent apoptotic pathway and inhibiting the expression of anti-apoptotic Bcl-2 family proteins in human osteosarcoma cells
por: CHENG, CHUN-HSIANG, et al.
Publicado: (2016)

Celastrol mediates autophagy and apoptosis via the ROS/JNK and Akt/mTOR signaling pathways in glioma cells
por: Liu, Xihong, et al.
Publicado: (2019)

Celastrol promotes chondrocyte autophagy by regulating mTOR expression
por: Dai, Siming, et al.
Publicado: (2022)

Metabolomics Reveals that Cysteine Metabolism Plays a Role in Celastrol-Induced Mitochondrial Apoptosis in HL-60 and NB-4 Cells
por: Chen, Minjian, et al.
Publicado: (2020)

Correction: Systematic identification of celastrol-binding proteins reveals that Shoc2 is inhibited by celastrol
Publicado: (2021)

The Synergistic Effects of Celastrol in combination with Tamoxifen on Apoptosis and Autophagy in MCF-7 Cells
por: Wang, Lijun, et al.
Publicado: (2021)

AICAR induces mitochondrial apoptosis in human osteosarcoma cells through an AMPK-dependent pathway
por: Morishita, Masayuki, et al.
Publicado: (2016)

Celastrol directly binds with VAMP7 and RAB7 to inhibit autophagy and induce apoptosis in preadipocytes
por: Liu, Chenshu, et al.
Publicado: (2023)

The development and evaluation of hyaluronic acid coated mitochondrial targeting liposomes for celastrol delivery
por: Xiao, Simeng, et al.
Publicado: (2023)

MiR-486 regulates cardiomyocyte apoptosis by p53-mediated BCL-2 associated mitochondrial apoptotic pathway
por: Sun, Yuhan, et al.
Publicado: (2017)

Protective effect of celastrol on myocardial ischemia–reperfusion injury
por: Li, Xiaoyan, et al.
Publicado: (2017)

Mesoporous tantalum oxide nanomaterials induced cardiovascular endothelial cell apoptosis via mitochondrial-endoplasmic reticulum stress apoptotic pathway
por: Jiao, Yuanyong, et al.
Publicado: (2022)

Canstatin induces apoptosis in gastric cancer xenograft growth in mice through the mitochondrial apoptotic pathway
por: Xing, Ya-Nan, et al.
Publicado: (2014)

Corilagin induces the apoptosis of hepatocellular carcinoma cells through the mitochondrial apoptotic and death receptor pathways
por: Deng, Yuan, et al.
Publicado: (2018)

Correction to: Celastrol mediates autophagy and apoptosis via the ROS/JNK and Akt/mTOR signaling pathways in glioma cells
por: Liu, Xihong, et al.
Publicado: (2019)

Apoptosis and apoptotic pathway in actinic prurigo by immunohistochemistry
por: Cuevas-González, Juan-Carlos, et al.
Publicado: (2016)

Celastrol induces ROS-mediated apoptosis via directly targeting peroxiredoxin-2 in gastric cancer cells
por: Chen, Xi, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_s14l1d2hb9u5rj0vhf0s7djuub