Cargando…

Genetics, diagnosis and management of colorectal cancer (Review)

Colorectal cancer (CRC) is the third most common type of cancer worldwide and a leading cause of cancer death. Surgery represents the mainstay of treatment in early cases but often patients are primarily diagnosed in an advanced stage of disease and sometimes also distant metastases are present. Neo...

Descripción completa

Detalles Bibliográficos
Autores principales:	DE ROSA, MARINA, PACE, UGO, REGA, DANIELA, COSTABILE, VALERIA, DURATURO, FRANCESCA, IZZO, PAOLA, DELRIO, PAOLO
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	D.A. Spandidos 2015
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4530899/ https://www.ncbi.nlm.nih.gov/pubmed/26151224 http://dx.doi.org/10.3892/or.2015.4108

Ejemplares similares

Characterisation of mesenchymal colon tumour-derived cells in tumourspheres as a model for colorectal cancer progression
por: Turano, Mimmo, et al.
Publicado: (2018)

Lithium chloride induces mesenchymal-to-epithelial reverting transition in primary colon cancer cell cultures
por: COSTABILE, VALERIA, et al.
Publicado: (2015)

Promising Colorectal Cancer Biomarkers for Precision Prevention and Therapy
por: Turano, Mimmo, et al.
Publicado: (2019)

Differential expression of PTEN gene correlates with phenotypic heterogeneity in three cases of patients showing clinical manifestations of PTEN hamartoma tumour syndrome
por: Paparo, Lorella, et al.
Publicado: (2013)

Genetics, diagnosis and treatment of Lynch syndrome: Old lessons and current challenges
por: Duraturo, Francesca, et al.
Publicado: (2019)

The Role of Colonoscopy in the Management of Individuals with Lynch Syndrome: A Narrative Review
por: D’Angelo, Valentina, et al.
Publicado: (2023)

Novel Implications in Molecular Diagnosis of Lynch Syndrome
por: Liccardo, Raffaella, et al.
Publicado: (2017)

The Epithelial to Mesenchymal Transition in Colorectal Cancer Progression: The Emerging Role of Succinate Dehydrogenase Alterations and Succinate Accumulation
por: Turano, Mimmo, et al.
Publicado: (2023)

A Potential Role of IL-6/IL-6R in the Development and Management of Colon Cancer
por: Turano, Mimmo, et al.
Publicado: (2021)

Hereditary Colorectal Cancer: State of the Art in Lynch Syndrome
por: Nolano, Antonio, et al.
Publicado: (2022)

Treatment of splenic flexure colon cancer: a comparison of three different surgical procedures: Experience of a high volume cancer center
por: Rega, Daniela, et al.
Publicado: (2019)

Novel MSH2 splice-site mutation in a young patient with Lynch syndrome
por: Liccardo, Raffaella, et al.
Publicado: (2018)

MiR-137 Targets the 3′ Untranslated Region of MSH2: Potential Implications in Lynch Syndrome-Related Colorectal Cancer
por: Liccardo, Raffaella, et al.
Publicado: (2021)

Evaluation of Tumor Response after Short-Course Radiotherapy and Delayed Surgery for Rectal Cancer
por: Rega, Daniela, et al.
Publicado: (2016)

Significance of rare variants in genes involved in the pathogenesis of Lynch syndrome
por: Liccardo, Raffaella, et al.
Publicado: (2022)

Electrochemotherapy of Primary Colon Rectum Cancer and Local Recurrence: Case Report and Prospective Analysis
por: Rega, Daniela, et al.
Publicado: (2022)

Novel variants of unknown significance in the PMS2 gene identified in patients with hereditary colon cancer
por: Liccardo, Raffaella, et al.
Publicado: (2019)

Incomplete Segregation of MSH6 Frameshift Variants with Phenotype of Lynch Syndrome
por: Liccardo, Raffaella, et al.
Publicado: (2017)

Contribution of Large Genomic Rearrangements in Italian Lynch Syndrome Patients: Characterization of a Novel Alu-Mediated Deletion
por: Duraturo, Francesca, et al.
Publicado: (2013)

Implications of Splicing Alterations in the Onset and Phenotypic Variability of a Family with Subclinical Manifestation of Peutz–Jeghers Syndrome: Bioinformatic and Molecular Evidence
por: Cerasuolo, Andrea, et al.
Publicado: (2020)

Watch and Wait Approach for Rectal Cancer Following Neoadjuvant Treatment: The Experience of a High Volume Cancer Center
por: Rega, Daniela, et al.
Publicado: (2021)

Beta catenin and cytokine pathway dysregulation in patients with manifestations of the "PTEN hamartoma tumor syndrome"
por: Galatola, Martina, et al.
Publicado: (2012)

MSH2 Overexpression Due to an Unclassified Variant in 3’-Untranslated Region in a Patient with Colon Cancer
por: Liccardo, Raffaella, et al.
Publicado: (2020)

Same MSH2 Gene Mutation But Variable Phenotypes in 2 Families With Lynch Syndrome: Two Case Reports and Review of Genotype-Phenotype Correlation
por: Liccardo, Raffaella, et al.
Publicado: (2018)

Germline Variants in MLH1 and ATM Genes in a Young Patient with MSI-H in a Precancerous Colonic Lesion
por: Nolano, Antonio, et al.
Publicado: (2023)

Synchronous robotic right hemicolectomy and subtotal gastrectomy
por: Carbone, Fabio, et al.
Publicado: (2020)

Lithium chloride increases sensitivity to photon irradiation treatment in primary mesenchymal colon cancer cells
por: Cammarota, Francesca, et al.
Publicado: (2020)

Peripheral myeloid-derived suppressor and T regulatory PD-1 positive cells predict response to neoadjuvant short-course radiotherapy in rectal cancer patients
por: Napolitano, Maria, et al.
Publicado: (2015)

Organ Sparing for Locally Advanced Rectal Cancer after Neoadjuvant Treatment Followed by Electrochemotherapy
por: Rega, Daniela, et al.
Publicado: (2021)

Multiple splenic hamartomas and familial adenomatous polyposis: a case report and review of the literature
por: Carlomagno, Nicola, et al.
Publicado: (2015)

Aflibercept or bevacizumab in combination with FOLFIRI as second-line treatment of mRAS metastatic colorectal cancer patients: the ARBITRATION study protocol
por: Ottaiano, Alessandro, et al.
Publicado: (2021)

New Deployable Expandable Electrodes in the Electroporation Treatment in a Pig Model: A Feasibility and Usability Preliminary Study
por: Izzo, Francesco, et al.
Publicado: (2020)

Problematic Internet Use and Emotional Dysregulation Among Young People: A Literature Review
por: Gioia, Francesca, et al.
Publicado: (2021)

Problematic Media Use among Children up to the Age of 10: A Systematic Literature Review
por: Rega, Valeria, et al.
Publicado: (2023)

Multidisciplinary Management of Retroperitoneal Sarcoma: Diagnosis, Prognostic Factors and Treatment
por: Carbone, Fabio, et al.
Publicado: (2021)

Genetic landscape of colorectal cancer patients manifesting tumor shrinkage during SARS-Cov-2 infection
por: Ottaiano, Alessandro, et al.
Publicado: (2022)

Plasma metabolomics, lipidomics and cytokinomics profiling predict disease recurrence in metastatic colorectal cancer patients undergoing liver resection
por: Costantini, Susan, et al.
Publicado: (2023)

Abbreviated MRI protocol for colorectal liver metastases: How the radiologist could work in pre surgical setting
por: Granata, Vincenza, et al.
Publicado: (2020)

Rubinstein-Taybi syndrome: clinical features, genetic basis, diagnosis, and management
por: Milani, Donatella, et al.
Publicado: (2015)

Risk factors for anastomotic leakage after anterior resection for rectal cancer (RALAR study): A nationwide retrospective study of the Italian Society of Surgical Oncology Colorectal Cancer Network Collaborative Group
por: Degiuli, Maurizio, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_adt536sg6vglk7s8ffvj6g736d