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Berberine-loaded solid lipid nanoparticles are concentrated in the liver and ameliorate hepatosteatosis in db/db mice

Berberine (BBR) shows very low plasma levels after oral administration due to its poor absorption by the gastrointestinal tract. We have previously demonstrated that BBR showed increased gastrointestinal absorption and enhanced antidiabetic effects in db/db mice after being entrapped into solid lipi...

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Detalles Bibliográficos
Autores principales:	Xue, Mei, Zhang, Liang, Yang, Ming-xing, Zhang, Wei, Li, Xiu-min, Ou, Zhi-min, Li, Zhi-peng, Liu, Su-huan, Li, Xue-jun, Yang, Shu-yu
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Dove Medical Press 2015
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4531046/ https://www.ncbi.nlm.nih.gov/pubmed/26346310 http://dx.doi.org/10.2147/IJN.S84565

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