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A systems-level “misunderstanding”: the plasma metabolome in Huntington’s disease
OBJECTIVE: Huntington’s disease (HD) is a rare neurodegenerative disease caused by the expansion of an N-terminal repeat in the huntingtin protein. The protein is expressed in all cells in the body; hence, peripheral tissues, such as blood, may recapitulate processes in the brain. The plasma metabol...
Autores principales: | Rosas, Herminia D, Doros, Gheorghe, Bhasin, Swati, Thomas, Beena, Gevorkian, Sona, Malarick, Keith, Matson, Wayne, Hersch, Steven M |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley & Sons, Ltd
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4531058/ https://www.ncbi.nlm.nih.gov/pubmed/26273688 http://dx.doi.org/10.1002/acn3.214 |
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