Interferon-α and the calcifying microangiopathy in Aicardi–Goutières syndrome

Aicardi–Goutières syndrome is a leukoencephalopathy with calcifications and increased cerebrospinal fluid interferon-α. The relation between interferon-α and brain pathology is poorly understood. We report a patient with mutations in the disease-associated gene SAMHD1. Neuropathology showed an exten...

Descripción completa

Detalles Bibliográficos
Autores principales: Klok, Melanie D, Bakels, Hannah S, Postma, Nienke L, van Spaendonk, Rosalina M L, van der Knaap, Marjo S, Bugiani, Marianna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Ltd 2015
Materias:
Brief Communications
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4531060/
https://www.ncbi.nlm.nih.gov/pubmed/26273690
http://dx.doi.org/10.1002/acn3.213

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4531060/
https://www.ncbi.nlm.nih.gov/pubmed/26273690
http://dx.doi.org/10.1002/acn3.213

Ejemplares similares