The HIV proteins Tat and Nef promote human bone marrow mesenchymal stem cell senescence and alter osteoblastic differentiation

To maintain bone mass turnover and bone mineral density (BMD), bone marrow (BM) mesenchymal stem cells (MSCs) are constantly recruited and subsequently differentiated into osteoblasts. HIV-infected patients present lower BMD than non-HIV infected individuals and a higher prevalence of osteopenia/ost...

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Detalles Bibliográficos
Autores principales: Beaupere, Carine, Garcia, Marie, Larghero, Jerome, Fève, Bruno, Capeau, Jacqueline, Lagathu, Claire
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Ltd 2015
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4531068/
https://www.ncbi.nlm.nih.gov/pubmed/25847297
http://dx.doi.org/10.1111/acel.12308

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4531068/
https://www.ncbi.nlm.nih.gov/pubmed/25847297
http://dx.doi.org/10.1111/acel.12308

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