Cargando…

The HIV proteins Tat and Nef promote human bone marrow mesenchymal stem cell senescence and alter osteoblastic differentiation

To maintain bone mass turnover and bone mineral density (BMD), bone marrow (BM) mesenchymal stem cells (MSCs) are constantly recruited and subsequently differentiated into osteoblasts. HIV-infected patients present lower BMD than non-HIV infected individuals and a higher prevalence of osteopenia/ost...

Descripción completa

Detalles Bibliográficos
Autores principales:	Beaupere, Carine, Garcia, Marie, Larghero, Jerome, Fève, Bruno, Capeau, Jacqueline, Lagathu, Claire
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley & Sons, Ltd 2015
Materias:	Original Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4531068/ https://www.ncbi.nlm.nih.gov/pubmed/25847297 http://dx.doi.org/10.1111/acel.12308

Ejemplares similares

SIV Infection and the HIV Proteins Tat and Nef Induce Senescence in Adipose Tissue and Human Adipose Stem Cells, Resulting in Adipocyte Dysfunction
por: Gorwood, Jennifer, et al.
Publicado: (2020)

Metformin alleviates stress-induced cellular senescence of aging human adipose stromal cells and the ensuing adipocyte dysfunction
por: Le Pelletier, Laura, et al.
Publicado: (2021)

Inhibition of Adipose Tissue Beiging by HIV Integrase Inhibitors, Dolutegravir and Bictegravir, Is Associated with Adipocyte Hypertrophy, Hypoxia, Elevated Fibrosis, and Insulin Resistance in Simian Adipose Tissue and Human Adipocytes
por: Ngono Ayissi, Kenza, et al.
Publicado: (2022)

Circadian Clock Genes Modulate Human Bone Marrow Mesenchymal Stem Cell Differentiation, Migration and Cell Cycle
por: Boucher, Helene, et al.
Publicado: (2016)

Study of the HIV-2 Env Cytoplasmic Tail Variability and Its Impact on Tat, Rev and Nef
por: Bakouche, Nordine, et al.
Publicado: (2013)

Overexpression of recombinant HIV-1 Subtype C Tat and Nef in a Salmonella vaccine vector
por: Chin’ombe, Nyasha, et al.
Publicado: (2013)

Hypoxia induces senescence of bone marrow mesenchymal stem cells via altered gut microbiota
por: Xing, Junyue, et al.
Publicado: (2018)

Osteoblastic differentiation of bone marrow mesenchymal stromal cells in Bruck Syndrome
por: Kaneto, Carla M., et al.
Publicado: (2016)

Proteomic Comparison of Bone Marrow Derived Osteoblasts and Mesenchymal Stem Cells
por: Aasebø, Elise, et al.
Publicado: (2021)

HIV-1 Nef alters podosomes and promotes the mesenchymal migration in human macrophages
por: Vérollet, Christel, et al.
Publicado: (2013)

Molecular Mechanisms of Glucocorticoid-Induced Insulin Resistance
por: Beaupere, Carine, et al.
Publicado: (2021)

SIVsm Tat, Rev, and Nef1: functional characteristics of r-GV internalization on isotypes, cytokines, and intracellular degradation
por: Sremac, Marinko, et al.
Publicado: (2010)

Contribution of Adipose Tissue to the Chronic Immune Activation and Inflammation Associated With HIV Infection and Its Treatment
por: Bourgeois, Christine, et al.
Publicado: (2021)

RANKL signaling in bone marrow mesenchymal stem cells negatively regulates osteoblastic bone formation
por: Chen, Xiao, et al.
Publicado: (2018)

Persistent DNA damage-induced premature senescence alters the functional features of human bone marrow mesenchymal stem cells
por: Minieri, Valentina, et al.
Publicado: (2015)

Radiation-Induced Osteocyte Senescence Alters Bone Marrow Mesenchymal Stem Cell Differentiation Potential via Paracrine Signaling
por: Xu, Linshan, et al.
Publicado: (2021)

Correction to: RANKL signaling in bone marrow mesenchymal stem cells negatively regulates osteoblastic bone formation
por: Chen, Xiao, et al.
Publicado: (2022)

Evidences of Early Senescence in Multiple Myeloma Bone Marrow Mesenchymal Stromal Cells
por: André, Thibaud, et al.
Publicado: (2013)

Rejuvenation of Senescent Bone Marrow Mesenchymal Stromal Cells by Pulsed Triboelectric Stimulation
por: Li, Gaocai, et al.
Publicado: (2021)

Differentiation of Bone Marrow Mesenchymal Stem Cells in Osteoblasts and Adipocytes and its Role in Treatment of Osteoporosis
por: Wang, Cheng, et al.
Publicado: (2016)

Efferocytosis by bone marrow mesenchymal stromal cells disrupts osteoblastic differentiation via mitochondrial remodeling
por: Quarato, Emily R., et al.
Publicado: (2023)

HIV antiretroviral drugs, dolutegravir, maraviroc and ritonavir-boosted atazanavir use different pathways to affect inflammation, senescence and insulin sensitivity in human coronary endothelial cells
por: Auclair, Martine, et al.
Publicado: (2020)

Bone Marrow Osteoblast Damage by Chemotherapeutic Agents
por: Rellick, Stephanie L., et al.
Publicado: (2012)

The Src inhibitor dasatinib accelerates the differentiation of human bone marrow-derived mesenchymal stromal cells into osteoblasts
por: Id Boufker, Hichame, et al.
Publicado: (2010)

ATF4 Promotes β-Catenin Expression and Osteoblastic Differentiation of Bone Marrow Mesenchymal Stem Cells
por: Yu, Shibing, et al.
Publicado: (2013)

The BMP signaling pathway enhances the osteoblastic differentiation of bone marrow mesenchymal stem cells in rats with osteoporosis
por: Zhao, Bin, et al.
Publicado: (2019)

Effects of inhibiting PDK-1 expression in bone marrow mesenchymal stem cells on osteoblast differentiation in vitro
por: Bai, Yiguang, et al.
Publicado: (2021)

Relationship between senescence in macaques and bone marrow mesenchymal stem cells and the molecular mechanism
por: Pan, Xing-hua, et al.
Publicado: (2019)

Study on the Dynamic Biological Characteristics of Human Bone Marrow Mesenchymal Stem Cell Senescence
por: Chen, Xiongbin, et al.
Publicado: (2019)

To Breathe or Not to Breathe: The Role of Oxygen in Bone Marrow-Derived Mesenchymal Stromal Cell Senescence
por: Gala, Dhir Niren, et al.
Publicado: (2021)

Proteomic Analysis of Hypoxia-Induced Senescence of Human Bone Marrow Mesenchymal Stem Cells
por: Mai, Liping, et al.
Publicado: (2021)

A Prospective Study of Bone Marrow Hematopoietic and Mesenchymal Stem Cells in Type 1 Gaucher Disease Patients
por: Lecourt, Séverine, et al.
Publicado: (2013)

Specific Biological Features of Adipose Tissue, and Their Impact on HIV Persistence
por: Bourgeois, Christine, et al.
Publicado: (2019)

Progerin Expression Induces Inflammation, Oxidative Stress and Senescence in Human Coronary Endothelial Cells
por: Bidault, Guillaume, et al.
Publicado: (2020)

Alterations in intracellular potassium concentration by HIV-1 and SIV Nef
por: Choi, Bongkun, et al.
Publicado: (2008)

Role of the Osteoblast Lineage in the Bone Marrow Hematopoietic Niches
por: Wu, Joy Y, et al.
Publicado: (2009)

Osteocytes regulate senescence of bone and bone marrow
por: Ding, Peng, et al.
Publicado: (2022)

Amphiregulin-EGFR Signaling Mediates the Migration of Bone Marrow Mesenchymal Progenitors toward PTH-Stimulated Osteoblasts and Osteocytes
por: Zhu, Ji, et al.
Publicado: (2012)

Para-Nonylphenol Impairs Osteogenic Differentiation of Rat Bone Marrow Mesenchymal Stem Cells by Influencing the Osteoblasts Mineralization
por: Abnosi, Mohammad Husein, et al.
Publicado: (2012)

Nanostructured TiO(2) Surfaces Promote Human Bone Marrow Mesenchymal Stem Cells Differentiation to Osteoblasts
por: Vercellino, Marco, et al.
Publicado: (2016)

Cannot write session to /tmp/vufind_sessions/sess_9q6je7ibe8q70sq38eqrqmos9s