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Lgr5(+) amacrine cells possess regenerative potential in the retina of adult mice

Current knowledge indicates that the adult mammalian retina lacks regenerative capacity. Here, we show that the adult stem cell marker, leucine-rich repeat-containing G-protein-coupled receptor 5 (Lgr5), is expressed in the retina of adult mice. Lgr5(+) cells are generated at late stages of retinal...

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Detalles Bibliográficos
Autores principales: Chen, Mengfei, Tian, Shenghe, Glasgow, Nathan G, Gibson, Gregory, Yang, Xiaoling, Shiber, Christen E, Funderburgh, James, Watkins, Simon, Johnson, Jon W, Schuman, Joel S, Liu, Hongjun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Ltd 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4531077/
https://www.ncbi.nlm.nih.gov/pubmed/25990970
http://dx.doi.org/10.1111/acel.12346