Cargando…
Haploinsufficiency of myostatin protects against aging-related declines in muscle function and enhances the longevity of mice
The molecular mechanisms behind aging-related declines in muscle function are not well understood, but the growth factor myostatin (MSTN) appears to play an important role in this process. Additionally, epidemiological studies have identified a positive correlation between skeletal muscle mass and l...
Autores principales: | Mendias, Christopher L, Bakhurin, Konstantin I, Gumucio, Jonathan P, Shallal-Ayzin, Mark V, Davis, Carol S, Faulkner, John A |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley & Sons, Ltd
2015
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4531085/ https://www.ncbi.nlm.nih.gov/pubmed/25808276 http://dx.doi.org/10.1111/acel.12339 |
Ejemplares similares
-
Exploring mechanisms of sex differences in longevity: lifetime ovary exposure and exceptional longevity in dogs
por: Waters, David J, et al.
Publicado: (2009) -
Exome sequencing of three cases of familial exceptional longevity
por: Cash, Timothy P, et al.
Publicado: (2014) -
Has gene duplication impacted the evolution of Eutherian longevity?
por: Doherty, Aoife, et al.
Publicado: (2016) -
Genetic interaction with temperature is an important determinant of nematode longevity
por: Miller, Hillary, et al.
Publicado: (2017) -
Immunochip analysis identifies association of the RAD50/IL13 region with human longevity
por: Flachsbart, Friederike, et al.
Publicado: (2016)