Cargando…
Narrowing the Gap: Preserving Repertoire Diversity Despite Clonal Selection during the CD4 T Cell Response
T cell immunity relies on the generation and maintenance of a diverse repertoire of T cell antigen receptors (TCRs). The strength of signaling emanating from the TCR dictates the fate of T cells during development, as well as during the immune response. Whereas development of new T cells in the thym...
Autores principales: | Merkenschlager, Julia, Kassiotis, George |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2015
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4531291/ https://www.ncbi.nlm.nih.gov/pubmed/26322045 http://dx.doi.org/10.3389/fimmu.2015.00413 |
Ejemplares similares
-
CD4(+) T Cell-Receptor Repertoire Diversity is Compromised in the Spleen but Not in the Bone Marrow of Aged Mice Due to Private and Sporadic Clonal Expansions
por: Shifrut, Eric, et al.
Publicado: (2013) -
Exploring the impact of clonal definition on B-cell diversity: implications for the analysis of immune repertoires
por: Pelissier, Aurelien, et al.
Publicado: (2023) -
Evaluation and comparison of adaptive immunity through analyzing the diversities and clonalities of T-cell receptor repertoires in the peripheral blood
por: Zhuo, Yue, et al.
Publicado: (2022) -
CD161(+) Tconv and CD161(+) Treg Share a Transcriptional and Functional Phenotype despite Limited Overlap in TCRβ Repertoire
por: Duurland, Chantal L., et al.
Publicado: (2017) -
Correlates of Follicular Helper Bias in the CD4 T Cell Response to a Retroviral Antigen
por: Danelli, Luca, et al.
Publicado: (2018)